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university of tampere: faculty of medicine and life sciences: research: flodström-tullberg - therdiab:
Lääketieteen ja biotieteiden tiedekuntaUniversity of TampereLääketieteen ja biotieteiden tiedekunta
Flodström-Tullberg - THERDIAB

Previous publications

Laitinen OH, Svedin E, Kapell S, Nurminen A, Hytönen VP, Flodström-Tullberg M
Enteroviral proteases: structure, host interactions and pathogenicity.
Rev Med Virol ;26(4)251-67, 2016
PMID

Brauner H, Hall HT, Flodström-Tullberg M, Kärre K, Höglund P, Johansson S
Depletion of IL-2 receptor β-positive cells protects from diabetes in non-obese diabetic mice.
Immunol Cell Biol ;94(2)177-84, 2016
PMID

Domsgen E, Lind K, Kong L, Hühn MH, Rasool O, van Kuppeveld F, Korsgren O, Lahesmaa R, Flodström-Tullberg M
An IFIH1 gene polymorphism associated with risk for autoimmunity regulates canonical antiviral defence pathways in Coxsackievirus infected human pancreatic islets.
Sci Rep ;2016
PMID

Schulte BM, Gielen PR, Kers-Rebel ED, Prosser AC, Lind K, Flodström-Tullberg M, Tack CJ, Elving LD, Adema GJ
Enterovirus Exposure Uniquely Discriminates Type 1 Diabetes Patients with a Homozygous from a Heterozygous Melanoma Differentiation-Associated Protein 5/Interferon Induced with Helicase C Domain 1 A946T Genotype.
Viral Immunol ;29(7)389-97, 2016
PMID

Pincikova T, Svedin E, Domsgen E, Flodström-Tullberg M, Hjelte L
Cystic fibrosis bronchial epithelial cells have impaired ability to activate vitamin D.
Acta Paediatr ;105(7)851-3, 2016
PMID

Lind K, Svedin E, Domsgen E, Kapell S, Laitinen O, Moll M, Flodström-Tullberg M
Coxsackievirus counters the host innate immune response by blocking type III interferon expression.
J Gen Virol ;97(6)1-12, 2016
PMID

Laiho JE, Oikarinen S, Oikarinen M, Larsson PG, Stone VM, Hober D, Oberste S, Flodström-Tullberg M, Isola J, Hyöty H
Application of bioinformatics in probe design enables detection of enteroviruses on different taxonomic levels by advanced in situ hybridization technology.
J Clin Virol 2015 ;69165-71
PMID

Larsson PG, Lakshmikanth T, Laitinen OH, Utorova R, Jacobson S, Oikarinen M, Domsgen E, Koivunen MR, Chaux P, Devard N, Lecouturier V, Almond J, Knip M, Hyöty H, Flodström-Tullberg M
A preclinical study on the efficacy and safety of a new vaccine against Coxsackievirus B1 reveals no risk for accelerated diabetes development in mouse models.
Diabetologia 2015 ;58(2)346-54
PMID

Ryall CL, Viloria K, Lhaf F, Walker AJ, King A, Jones P, Mackintosh D, McNeice R, Kocher H, Flodstrom-Tullberg M, Edling C, Hill NJ
Novel role for matricellular proteins in the regulation of islet β cell survival: the effect of SPARC on survival, proliferation, and signaling.
J Biol Chem 2014 ;289(44)30614-24
PMID

Edlund A, Esguerra JL, Wendt A, Flodström-Tullberg M, Eliasson L
CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells.
BMC Med 2014 ;1287
PMID

Richardson SJ, Leete P, Dhayal S, Russell MA, Oikarinen M, Laiho JE, Svedin E, Lind K, Rosenling T, Chapman N, Bone AJ, Foulis AK, Frisk G, Flodström-Tullberg M, Hober D, Hyoty H, Pugliese A, Morgan NG
Detection of enterovirus in the islet cells of patients with type 1 diabetes: what do we learn from immunohistochemistry? Reply to Hansson SF, Korsgren S, Pontén F et al [letter].
Diabetologia 2014 ;57(3)647-9
PMID

Richardson SJ, Leete P, Dhayal S, Russell MA, Oikarinen M, Laiho JE, Svedin E, Lind K, Rosenling T, Chapman N, Bone AJ, , Foulis AK, Frisk G, Flodstrom-Tullberg M, Hober D, Hyoty H, Morgan NG
Evaluation of the fidelity of immunolabelling obtained with clone 5D8/1, a monoclonal antibody directed against the enteroviral capsid protein, VP1, in human pancreas.
Diabetologia 2014 ;57(2)392-401
PMID

Ghazarian L, Diana J, Beaudoin L, Larsson PG, Puri RK, van Rooijen N, Flodström-Tullberg M, Lehuen A
Protection against type 1 diabetes upon Coxsackievirus B4 infection and iNKT-cell stimulation: role of suppressive macrophages.
Diabetes 2013 ;62(11)3785-96
PMID

Lind K, Richardson SJ, Leete P, Morgan NG, Korsgren O, Flodström-Tullberg M
Induction of an antiviral state and attenuated coxsackievirus replication in type III interferon-treated primary human pancreatic islets.
J Virol 2013 ;87(13)7646-54
PMID

Kumagai-Braesch M, Jacobson S, Mori H, Jia X, Takahashi T, Wernerson A, Flodström-Tullberg M, Tibell A
The TheraCyte™ device protects against islet allograft rejection in immunized hosts.
Cell Transplant 2013 ;22(7)1137-46
PMID

Zadjali F, Santana-Farre R, Vesterlund M, Carow B, Mirecki-Garrido M, Hernandez-Hernandez I, Flodström-Tullberg M, Parini P, Rottenberg M, Norstedt G, Fernandez-Perez L, Flores-Morales A
SOCS2 deletion protects against hepatic steatosis but worsens insulin resistance in high-fat-diet-fed mice.
FASEB J 2012 ;26(8)3282-91
PMID

Solomon M, Flodström-Tullberg M, Sarvetnick N
Beta-cell specific expression of suppressor of cytokine signaling-1 (SOCS-1) delays islet allograft rejection by down-regulating Interferon Regulatory Factor-1 (IRF-1) signaling.
Transpl Immunol 2011 ;24(3)181-8
PMID

Björkström NK, Riese P, Heuts F, Andersson S, Fauriat C, Ivarsson MA, Björklund AT, Flodström-Tullberg M, Michaëlsson J, Rottenberg ME, Guzmán CA, Ljunggren HG, Malmberg KJ
Expression patterns of NKG2A, KIR, and CD57 define a process of CD56dim NK-cell differentiation uncoupled from NK-cell education.
Blood 2010 ;116(19)3853-64
PMID

Hühn MH, McCartney SA, Lind K, Svedin E, Colonna M, Flodström-Tullberg M
Melanoma differentiation-associated protein-5 (MDA-5) limits early viral replication but is not essential for the induction of type 1 interferons after Coxsackievirus infection.
Virology 2010 ;401(1)42-8
PMID

Brauner H, Elemans M, Lemos S, Broberger C, Holmberg D, Flodström-Tullberg M, Kärre K, Höglund P
Distinct phenotype and function of NK cells in the pancreas of nonobese diabetic mice.
J Immunol 2010 ;184(5)2272-80
PMID

Flodström-Tullberg M, Bryceson YT, Shi FD, Höglund P, Ljunggren HG
Natural killer cells in human autoimmunity.
Curr Opin Immunol 2009 ;21(6)634-40
PMID

McGuire HM, Vogelzang A, Hill N, Flodström-Tullberg M, Sprent J, King C
Loss of parity between IL-2 and IL-21 in the NOD Idd3 locus.
Proc Natl Acad Sci U S A 2009 ;106(46)19438-43
PMID

Zaitseva II, Hultcrantz M, Sharoyko V, Flodström-Tullberg M, Zaitsev SV, Berggren PO
Suppressor of cytokine signaling-1 inhibits caspase activation and protects from cytokine-induced beta cell death.
Cell Mol Life Sci 2009 ;66(23)3787-95
PMID

 
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