Computational Biology Group started at the IBT (nowadays BMT) in the beginning of 2013. Our research is based on systems biology methodology to study biological phenomena. Our two main research areas are the applied biomedical research and development of computational data analysis tools and models. Using computational systems biology methods, we work with a number of biological systems in collaboration with experimental groups, ranging from cancer to immunology and cell differentiation. Our data-driven approaches often stem from acquiring combinations of high-throughput measurement data from genomic, epigenomic and transcriptomic levels with the goal to gain understanding of the gene regulation at systems level through these data. Novel hypotheses made by the computational methods are further studied in collaboration with experimental laboratories. Recently, we have also started our own line of experimental cancer research to enable us to more efficiently steer the research on-site. We also interrogate biological systems from theoretical standpoints using models such as Boolean networks. Our work in theoretical models is focused on the fundamental principles of biological systems, such as the information processing and the effect of structural constrains to dynamics.
Integration of computational models with multimodal experimental data will lead to deeper understanding of biological processes and human diseases. Ultimately paving the way to personalized medicine.
Current sources of External funding: Academy of Finland, Finnish Funding Agency for Technology and Innovation (TEKES), Emil Aaltonen Foundation, Sigrid Juselius Foundation
The PCRC brings together groups from all units of UTA in the campus; BioMediTech, School of Medicine (MED), and School of Health Sciences (HES). Also, Tampere University Hospital, Fimlab Ltd, and a unit from Tampere University of Technology (TUT) are closely affiliated to the research center.
Home page: Prostate Cancer Research Center
Computational Biology Group is in charge for the organization of the curriculum of the international Master's Degree Programme in Bioinformatics at the University of Tampere.