To page body
university of tampere: faculty of medicine and life sciences: research: mika rämet - experimental immunology:
Lääketieteen ja biotieteiden tiedekuntaUniversity of TampereLääketieteen ja biotieteiden tiedekunta
Mika Rämet - Experimental Immunology

Previous publications

Salminen TS, Rämet M
Pickle Flavors Relish in Drosophila Immunity.
Cell Host Microbe ;20(3)273-274, 2016
PMID

Schmid MR, Anderl I, Vo HT, Valanne S, Yang H, Kronhamn J, Rämet M, Rusten TE, Hultmark D
Genetic Screen in Drosophila Larvae Links ird1 Function to Toll Signaling in the Fat Body and Hemocyte Motility.
PLoS One ;11(7)e0159473, 2016
PMID

Myllymäki H, Bäuerlein CA, Rämet M
The Zebrafish Breathes New Life into the Study of Tuberculosis.
Front Immunol ;2016
PMID

Anderl I, Vesala L, Ihalainen TO, Vanha-Aho LM, Andó I, Rämet M, Hultmark D
Transdifferentiation and Proliferation in Two Distinct Hemocyte Lineages in Drosophila melanogaster Larvae after Wasp Infection.
PLoS Pathog ;12(7)e1005746, 2016
PMID

Vanha-Aho LM, Valanne S, Rämet M
Cytokines in Drosophila immunity.
Immunol Lett ;2016
PMID

Utriainen M, Rämet M
[Immuno-oncology--silver bullets or mass destruction weapons?].
Duodecim ;132(8)721-8, 2016
PMID

Oksanen KE, Myllymäki H, Ahava MJ, Mäkinen L, Parikka M, Rämet M
DNA vaccination boosts Bacillus Calmette-Guérin protection against mycobacterial infection in zebrafish.
Dev Comp Immunol ;54(1)89-96, 2016
PMID

Syrjänen L, Valanne S, Kuuslahti M, Tuomela T, Sriram A, Sanz A, Jacobs HT, Rämet M, Parkkila S
β carbonic anhydrase is required for female fertility in Drosophila melanogaster.
Front Zool 2015 ;1219
PMID

Aspatwar A, Tolvanen ME, Ojanen MJ, Barker HR, Saralahti AK, Bäuerlein CA, Ortutay C, Pan P, Kuuslahti M, Parikka M, Rämet M, Parkkila S
Inactivation of ca10a and ca10b Genes Leads to Abnormal Embryonic Development and Alters Movement Pattern in Zebrafish.
PLoS One 2015 ;10(7)e0134263
PMID

Karjalainen MK, Ojaniemi M, Haapalainen AM, Mahlman M, Salminen A, Huusko JM, Määttä TA, Kaukola T, Anttonen J, Ulvila J, Haataja R, Teramo K, Kingsmore SF, Palotie A, Muglia LJ, Rämet M, Hallman M
CXCR3 Polymorphism and Expression Associate with Spontaneous Preterm Birth.
J Immunol 2015 ;195(5)2187-98
PMID

Myllymäki H, Niskanen M, Oksanen KE, Rämet M
Animal models in tuberculosis research - where is the beef?
Expert Opin Drug Discov 2015 ;10(8)871-83
PMID

Mahlman M, Huusko JM, Karjalainen MK, Kaukola T, Marttila R, Ojaniemi M, Haataja R, Lavoie PM, Rämet M, Hallman M,
Genes Encoding Vascular Endothelial Growth Factor A (VEGF-A) and VEGF Receptor 2 (VEGFR-2) and Risk for Bronchopulmonary Dysplasia.
Neonatology 2015 ;108(1)53-9
PMID

Vanha-Aho LM, Anderl I, Vesala L, Hultmark D, Valanne S, Rämet M
Edin Expression in the Fat Body Is Required in the Defense Against Parasitic Wasps in Drosophila melanogaster.
PLoS Pathog 2015 ;11(5)e1004895
PMID

Ojanen MJ, Turpeinen H, Cordova ZM, Hammarén MM, Harjula SK, Parikka M, Rämet M, Pesu M
The proprotein convertase subtilisin/kexin furinA regulates zebrafish host response against Mycobacterium marinum.
Infect Immun 2015 ;83(4)1431-42
PMID

Huusko JM, Karjalainen MK, Mahlman M, Haataja R, Kari MA, Andersson S, Toldi G, Tammela O, Rämet M, Lavoie PM, Hallman M,
A study of genes encoding cytokines (IL6, IL10, TNF), cytokine receptors (IL6R, IL6ST), and glucocorticoid receptor (NR3C1) and susceptibility to bronchopulmonary dysplasia.
BMC Med Genet 2014 ;15120
PMID

Schmid MR, Anderl I, Vesala L, Vanha-aho LM, Deng XJ, Rämet M, Hultmark D
Control of Drosophila blood cell activation via Toll signaling in the fat body.
PLoS One 2014 ;9(8)e102568
PMID

Hammarén MM, Oksanen KE, Nisula HM, Luukinen BV, Pesu M, Rämet M, Parikka M
Adequate Th2-type response associates with restricted bacterial growth in latent mycobacterial infection of zebrafish.
PLoS Pathog 2014 ;10(6)e1004190
PMID

Kuuluvainen E, Hakala H, Havula E, Sahal Estimé M, Rämet M, Hietakangas V, Mäkelä TP
Cyclin-dependent kinase 8 module expression profiling reveals requirement of mediator subunits 12 and 13 for transcription of Serpent-dependent innate immunity genes in Drosophila.
J Biol Chem 2014 ;289(23)16252-61
PMID

Myllymäki H, Valanne S, Rämet M
The Drosophila imd signaling pathway.
J Immunol 2014 ;192(8)3455-62
PMID

Huusko JM, Mahlman M, Karjalainen MK, Kaukola T, Haataja R, Marttila R, Toldi G, Szabó M, Kingsmore SF, Rämet M, Lavoie PM, Hallman M,
Polymorphisms of the gene encoding Kit ligand are associated with bronchopulmonary dysplasia.
Pediatr Pulmonol 2014 ;
PMID

Saralahti A, Piippo H, Parikka M, Henriques-Normark B, Rämet M, Rounioja S
Adult zebrafish model for pneumococcal pathogenesis.
Dev Comp Immunol 2014 ;42(2)345-53
PMID

Rämet M, Hultmark D
Drosophila immunity--glorious past, dynamic present and exciting future.
Dev Comp Immunol 2014 ;42(1)1-2
PMID

Taskinen B, Zmurko J, Ojanen M, Kukkurainen S, Parthiban M, Määttä JA, Leppiniemi J, Jänis J, Parikka M, Turpeinen H, Rämet M, Pesu M, Johnson MS, Kulomaa MS, Airenne TT, Hytönen VP
Zebavidin - an avidin-like protein from zebrafish.
PLoS One 2013 ;8(10)e77207
PMID

Turpeinen H, Oksanen A, Kivinen V, Kukkurainen S, Uusimäki A, Rämet M, Parikka M, Hytönen VP, Nykter M, Pesu M
Proprotein Convertase Subtilisin/Kexin Type 7 (PCSK7) Is Essential for the Zebrafish Development and Bioavailability of Transforming Growth Factor β1a (TGFβ1a).
J Biol Chem 2013 ;288(51)36610-23
PMID

Oksanen KE, Halfpenny NJ, Sherwood E, Harjula SK, Hammarén MM, Ahava MJ, Pajula ET, Lahtinen MJ, Parikka M, Rämet M
An adult zebrafish model for preclinical tuberculosis vaccine development.
Vaccine 2013 ;31(45)5202-9
PMID

Junttila I, Meri S, Rämet M
[Inflammasome--essential regulator of the inflammatory reaction].
Duodecim 2013 ;129(7)705-11
PMID

Valanne S, Rämet M
Uracil debases pathogenic but not commensal bacteria.
Cell Host Microbe 2013 ;13(5)505-6
PMID

Aspatwar A, Tolvanen ME, Jokitalo E, Parikka M, Ortutay C, Harjula SK, Rämet M, Vihinen M, Parkkila S
Abnormal cerebellar development and ataxia in CARP VIII morphant zebrafish.
Hum Mol Genet 2013 ;22(3)417-32
PMID

Lohi O, Parikka M, Rämet M
The zebrafish as a model for paediatric diseases.
Acta Paediatr 2013 ;102(2)104-10
PMID

Parikka M, Hammarén MM, Harjula SK, Halfpenny NJ, Oksanen KE, Lahtinen MJ, Pajula ET, Iivanainen A, Pesu M, Rämet M
Mycobacterium marinum causes a latent infection that can be reactivated by gamma irradiation in adult zebrafish.
PLoS Pathog 2012 ;8(9)e1002944
PMID

Patterson H, Saralahti A, Parikka M, Dramsi S, Trieu-Cuot P, Poyart C, Rounioja S, Rämet M
Adult zebrafish model of bacterial meningitis in Streptococcus agalactiae infection.
Dev Comp Immunol 2012 ;38(3)447-55
PMID

Teittinen KJ, Grönroos T, Parikka M, Junttila S, Uusimäki A, Laiho A, Korkeamäki H, Kurppa K, Turpeinen H, Pesu M, Gyenesei A, Rämet M, Lohi O
SAP30L (Sin3A-associated protein 30-like) is involved in regulation of cardiac development and hematopoiesis in zebrafish embryos.
J Cell Biochem 2012 ;113(12)3843-52
PMID

Teittinen KJ, Grönroos T, Parikka M, Rämet M, Lohi O
The zebrafish as a tool in leukemia research.
Leuk Res 2012 ;36(9)1082-8
PMID

Sampson CJ, Valanne S, Fauvarque MO, Hultmark D, Rämet M, Williams MJ
The RhoGEF Zizimin-related acts in the Drosophila cellular immune response via the Rho GTPases Rac2 and Cdc42.
Dev Comp Immunol 2012 ;38(1)160-8
PMID

Rämet M
The fruit fly Drosophila melanogaster unfolds the secrets of innate immunity.
Acta Paediatr 2012 ;101(9)900-5
PMID

Vanha-Aho LM, Kleino A, Kaustio M, Ulvila J, Wilke B, Hultmark D, Valanne S, Rämet M
Functional characterization of the infection-inducible peptide Edin in Drosophila melanogaster.
PLoS One 2012 ;7(5)e37153
PMID

Grönholm J, Kaustio M, Myllymäki H, Kallio J, Saarikettu J, Kronhamn J, Valanne S, Silvennoinen O, Rämet M
Not4 enhances JAK/STAT pathway-dependent gene expression in Drosophila and in human cells.
FASEB J 2012 ;26(3)1239-50
PMID

Valanne S, Kallio J, Kleino A, Rämet M
Large-scale RNAi screens add both clarity and complexity to Drosophila NF-κB signaling.
Dev Comp Immunol 2012 ;37(1)9-18
PMID

Rounioja S, Saralahti A, Rantala L, Parikka M, Henriques-Normark B, Silvennoinen O, Rämet M
Defense of zebrafish embryos against Streptococcus pneumoniae infection is dependent on the phagocytic activity of leukocytes.
Dev Comp Immunol 2012 ;36(2)342-8
PMID

Valanne S, Rämet M
[Fruit fly--genetically excellent model animal for research].
Duodecim 2011 ;127(19)2063-71
PMID

Ulvila J, Vanha-Aho LM, Rämet M
Drosophila phagocytosis - still many unknowns under the surface.
APMIS 2011 ;119(10)651-62
PMID

Valanne S, Wang JH, Rämet M
The Drosophila Toll signaling pathway.
J Immunol 2011 ;186(2)649-56
PMID

Ulvila J, Vanha-aho LM, Kleino A, Vähä-Mäkilä M, Vuoksio M, Eskelinen S, Hultmark D, Kocks C, Hallman M, Parikka M, Rämet M
Cofilin regulator 14-3-3zeta is an evolutionarily conserved protein required for phagocytosis and microbial resistance.
J Leukoc Biol 2011 ;89(5)649-59
PMID

Rämet M, Korppi M, Hallman M
Pattern recognition receptors and genetic risk for rsv infection: value for clinical decision-making?
Pediatr Pulmonol 2011 ;46(2)101-10
PMID

Wang JH, Valanne S, Rämet M
Drosophila as a model for antiviral immunity.
World J Biol Chem 2010 ;1(5)151-9
PMID

Hyvärinen J, Parikka M, Sormunen R, Rämet M, Tryggvason K, Kivirikko KI, Myllyharju J, Koivunen P
Deficiency of a transmembrane prolyl 4-hydroxylase in the zebrafish leads to basement membrane defects and compromised kidney function.
J Biol Chem 2010 ;285(53)42023-32
PMID

Rämet M, Hallman M
Surfactant proteins and respiratory syncytial virus.
J Pediatr 2010 ;157(5)866; author reply 866-7
PMID

Kallio J, Myllymäki H, Grönholm J, Armstrong M, Vanha-aho LM, Mäkinen L, Silvennoinen O, Valanne S, Rämet M
Eye transformer is a negative regulator of Drosophila JAK/STAT signaling.
FASEB J 2010 ;24(11)4467-79
PMID

Grönholm J, Ungureanu D, Vanhatupa S, Rämet M, Silvennoinen O
Sumoylation of Drosophila transcription factor STAT92E.
J Innate Immun 2010 ;2(6)618-24
PMID

Löfgren J, Marttila R, Renko M, Rämet M, Hallman M
Toll-like receptor 4 Asp299Gly polymorphism in respiratory syncytial virus epidemics.
Pediatr Pulmonol 2010 ;45(7)687-92
PMID

Valanne S, Myllymäki H, Kallio J, Schmid MR, Kleino A, Murumägi A, Airaksinen L, Kotipelto T, Kaustio M, Ulvila J, Esfahani SS, Engström Y, Silvennoinen O, Hultmark D, Parikka M, Rämet M
Genome-wide RNA interference in Drosophila cells identifies G protein-coupled receptor kinase 2 as a conserved regulator of NF-kappaB signaling.
J Immunol 2010 ;184(11)6188-98
PMID

Kleino A, Myllymäki H, Kallio J, Vanha-aho LM, Oksanen K, Ulvila J, Hultmark D, Valanne S, Rämet M
Pirk is a negative regulator of the Drosophila Imd pathway.
J Immunol 2008 ;180(8)5413-22
PMID

Valanne S, Kleino A, Myllymäki H, Vuoristo J, Rämet M
Iap2 is required for a sustained response in the Drosophila Imd pathway.
Dev Comp Immunol 2007 ;31(10)991-1001
PMID

Ulvila J, Parikka M, Kleino A, Sormunen R, Ezekowitz RA, Kocks C, Rämet M
Double-stranded RNA is internalized by scavenger receptor-mediated endocytosis in Drosophila S2 cells.
J Biol Chem 2006 ;281(20)14370-5
PMID

Kocks C, Cho JH, Nehme N, Ulvila J, Pearson AM, Meister M, Strom C, Conto SL, Hetru C, Stuart LM, Stehle T, Hoffmann JA, Reichhart JM, Ferrandon D, Rämet M, Ezekowitz RA
Eater, a transmembrane protein mediating phagocytosis of bacterial pathogens in Drosophila.
Cell 2005 ;123(2)335-46
PMID

Kleino A, Valanne S, Ulvila J, Kallio J, Myllymäki H, Enwald H, Stöven S, Poidevin M, Ueda R, Hultmark D, Lemaitre B, Rämet M
Inhibitor of apoptosis 2 and TAK1-binding protein are components of the Drosophila Imd pathway.
EMBO J 2005 ;24(19)3423-34
PMID

Kallio J, Leinonen A, Ulvila J, Valanne S, Ezekowitz RA, Rämet M
Functional analysis of immune response genes in Drosophila identifies JNK pathway as a regulator of antimicrobial peptide gene expression in S2 cells.
Microbes Infect 2005 ;7(5-6)811-9
PMID

Rämet M
[Innate immunity and infections in children].
Duodecim 2004 ;120(5)553-60
PMID

Marttila R, Haataja R, Rämet M, Pokela ML, Tammela O, Hallman M
Surfactant protein A gene locus and respiratory distress syndrome in Finnish premature twin pairs.
Ann Med 2003 ;35(5)344-52
PMID

Pearson AM, Baksa K, Rämet M, Protas M, McKee M, Brown D, Ezekowitz RA
Identification of cytoskeletal regulatory proteins required for efficient phagocytosis in Drosophila.
Microbes Infect 2003 ;5(10)815-24
PMID

Rämet ME, Rämet M, Lu Q, Nickerson M, Savolainen MJ, Malzone A, Karas RH
High-density lipoprotein increases the abundance of eNOS protein in human vascular endothelial cells by increasing its half-life.
J Am Coll Cardiol 2003 ;41(12)2288-97
PMID

Marttila R, Haataja R, Rämet M, Löfgren J, Hallman M
Surfactant protein B polymorphism and respiratory distress syndrome in premature twins.
Hum Genet 2003 ;112(1)18-23
PMID

Lahti M, Lofgren J, Marttila R, Renko M, Klaavuniemi T, Haataja R, Ramet M, Hallman M
Surfactant protein D gene polymorphism associated with severe respiratory syncytial virus infection.
Pediatr Res 2002 ;51(6)696-9
PMID

Rämet M, Manfruelli P, Pearson A, Mathey-Prevot B, Ezekowitz RA
Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli.
Nature 2002 ;416(6881)644-8
PMID

Löfgren J, Rämet M, Renko M, Marttila R, Hallman M
Association between surfactant protein A gene locus and severe respiratory syncytial virus infection in infants.
J Infect Dis 2002 ;185(3)283-9
PMID

Rämet M, Lanot R, Zachary D, Manfruelli P
JNK signaling pathway is required for efficient wound healing in Drosophila.
Dev Biol 2002 ;241(1)145-56
PMID

Ramet M, Pearson A, Manfruelli P, Li X, Koziel H, Gobel V, Chung E, Krieger M, Ezekowitz RA
Drosophila scavenger receptor CI is a pattern recognition receptor for bacteria.
Immunity 2001 ;15(6)1027-38
PMID

Haataja R, Marttila R, Uimari P, Lofgren J, Ramet M, Hallman M
Respiratory distress syndrome: evaluation of genetic susceptibility and protection by transmission disequilibrium test.
Hum Genet 2001 ;109(3)351-5
PMID

Floros J, Fan R, Matthews A, DiAngelo S, Luo J, Nielsen H, Dunn M, Gewolb IH, Koppe J, van Sonderen L, Farri-Kostopoulos L, Tzaki M, Ramet M, Merrill J
Family-based transmission disequilibrium test (TDT) and case-control association studies reveal surfactant protein A (SP-A) susceptibility alleles for respiratory distress syndrome (RDS) and possible race differences.
Clin Genet 2001 ;60(3)178-87
PMID

Hallman M, Ramet M, Ezekowitz RA
Toll-like receptors as sensors of pathogens.
Pediatr Res 2001 ;50(3)315-21
PMID

Hallman M, Glumoff V, Ramet M
Surfactant in respiratory distress syndrome and lung injury.
Comp Biochem Physiol A Mol Integr Physiol 2001 ;129(1)287-94
PMID

Ramet M, Lofgren J, Alho OP, Hallman M
Surfactant protein-A gene locus associated with recurrent otitis media.
J Pediatr 2001 ;138(2)266-8
PMID

Bruyere K, Bermond F, Bouquet R, Caire Y, Ramet M, Voiglio E
Human maxilla bone response to 30 degrees oriented impacts and comparison with frontal bone impacts.
Annu Proc Assoc Adv Automot Med 2000 ;44219-34
PMID

Ramet M, Haataja R, Marttila R, Hamalainen AM, Knip M, Hallman M
Human surfactant protein--A gene locus for genetic studies in the Finnish population.
Dis Markers 2000 ;16(3-4)119-24
PMID

Haataja R, Ramet M, Marttila R, Hallman M
Surfactant proteins A and B as interactive genetic determinants of neonatal respiratory distress syndrome.
Hum Mol Genet 2000 ;9(18)2751-60
PMID

Ramet M, Haataja R, Marttila R, Floros J, Hallman M
Association between the surfactant protein A (SP-A) gene locus and respiratory-distress syndrome in the Finnish population.
Am J Hum Genet 2000 ;66(5)1569-79
PMID

DiAngelo S, Lin Z, Wang G, Phillips S, Ramet M, Luo J, Floros J
Novel, non-radioactive, simple and multiplex PCR-cRFLP methods for genotyping human SP-A and SP-D marker alleles.
Dis Markers 1999 ;15(4)269-81
PMID

 
Faculty of Medicine and Life Sciences
Arvo Ylpön katu 34
33520 Tampere, Finland
Maintained by: webmaster@biomeditech.fi
Last update: 12.8.2014 13.39 Muokkaa

University of Tampere
+358 3 355 111
registry@uta.fi


FINEEC Audited HR Excellence in Research

THE UNIVERSITY
Research
Admissions
Studies
News
Cooperation and Services
About Us

CURRENT ISSUES
Research & Study
Tampere3
Vacancies

SERVICES
Administration
Career Services
Finnish Social Science Data Archive
Centre for International Education
IT services
Language Centre
Language Services
Library
Registrar's Office
Registry
Sports Activities
» more

STUDIES
Teaching schedules
Curricula guides
Student's Desktop

ONLINE SERVICES
Andor search
Renew your loans
UTA intranet
Office 365 webmail
Uta webmail
Moodle
NettiOpsu
NettiKatti
TamPub
Electronic exam service
Examination results