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IBT julkaisut 1999

NOTE: This list is not exhaustive because it has been collected by an automatic procedure from PubMed. It may also contain publications not related to IMT or Regea authors (authors having the same name). The same publication may also appear more than once in case several research groups have participated in the writing.
Riikonen P, Vihinen M
MUTbase: maintenance and analysis of distributed mutation databases.
Bioinformatics 1999 ;15(10)852-9
PMID

Okoh MP, Vihinen M
Pleckstrin homology domains of tec family protein kinases.
Biochem Biophys Res Commun 1999 ;265(1)151-7
PMID

Vihinen M, Kwan SP, Lester T, Ochs HD, Resnick I, Valiaho J, Conley ME, Smith CI
Mutations of the human BTK gene coding for bruton tyrosine kinase in X-linked agammaglobulinemia.
Hum Mutat 1999 ;13(4)280-5
PMID

Makiniemi M, Pospiech H, Kilpelainen S, Jokela M, Vihinen M, Syvaoja JE
A novel family of DNA-polymerase-associated B subunits.
Trends Biochem Sci 1999 ;24(1)14-6
PMID

Stenberg KA, Riikonen PT, Vihinen M
KinMutBase, a database of human disease-causing protein kinase mutations.
Nucleic Acids Res 1999 ;27(1)362-4
PMID

Isola J
[The Young Scientist award to Tapio Visakorpi].
Duodecim 1999 ;115(24)2717-8
PMID

Pan Y, Kytölä S, Farnebo F, Wang N, Lui WO, Nupponen N, Isola J, Visakorpi T, Bergerheim US, Larsson C
Characterization of chromosomal abnormalities in prostate cancer cell lines by spectral karyotyping.
Cytogenet Cell Genet 1999 ;87(3-4)225-32
PMID

Isola J, Chu L, DeVries S, Matsumura K, Chew K, Ljung BM, Waldman FM
Genetic alterations in ERBB2-amplified breast carcinomas.
Clin Cancer Res 1999 ;5(12)4140-5
PMID

Saarenmaa I, Salminen T, Geiger U, Holli K, Isola J, Kärkkäinen A, Pakkanen J, Piironen A, Salo A, Hakama M
The visibility of cancer on earlier mammograms in a population-based screening programme.
Eur J Cancer 1999 ;35(7)1118-22
PMID

Järvinen TA, Tanner M, Bärlund M, Borg A, Isola J
Characterization of topoisomerase II alpha gene amplification and deletion in breast cancer.
Genes Chromosomes Cancer 1999 ;26(2)142-50
PMID

Järvinen TA, Jozsa L, Kannus P, Järvinen TL, Kvist M, Hurme T, Isola J, Kalimo H, Järvinen M
Mechanical loading regulates tenascin-C expression in the osteotendinous junction.
J Cell Sci 1999 ;112 Pt 183157-66
PMID

Nupponen NN, Porkka K, Kakkola L, Tanner M, Persson K, Borg A, Isola J, Visakorpi T
Amplification and overexpression of p40 subunit of eukaryotic translation initiation factor 3 in breast and prostate cancer.
Am J Pathol 1999 ;154(6)1777-83
PMID

Miettinen H, Kononen J, Sallinen P, Alho H, Helen P, Helin H, Kalimo H, Paljärvi L, Isola J, Haapasalo H
CDKN2/p16 predicts survival in oligodendrogliomas: comparison with astrocytomas.
J Neurooncol 1999 ;41(3)205-11
PMID

Persson K, Pandis N, Mertens F, Borg A, Baldetorp B, Killander D, Isola J
Chromosomal aberrations in breast cancer: a comparison between cytogenetics and comparative genomic hybridization.
Genes Chromosomes Cancer 1999 ;25(2)115-22
PMID

Karhu R, Rummukainen J, Lörch T, Isola J
Four-color CGH: a new method for quality control of comparative genomic hybridization.
Genes Chromosomes Cancer 1999 ;24(2)112-8
PMID

DiAngelo S, Lin Z, Wang G, Phillips S, Ramet M, Luo J, Floros J
Novel, non-radioactive, simple and multiplex PCR-cRFLP methods for genotyping human SP-A and SP-D marker alleles.
Dis Markers 1999 ;15(4)269-81
PMID

Lehtinen SK, Spelbrink JN, Jacobs HT
Heteroplasmic segregation associated with trisomy-9 in cultured human cells.
Somat Cell Mol Genet 1999 ;25(5-6)263-74
PMID

Toompuu M, Tiranti V, Zeviani M, Jacobs HT
Molecular phenotype of the np 7472 deafness-associated mitochondrial mutation in osteosarcoma cell cybrids.
Hum Mol Genet 1999 ;8(12)2275-83
PMID

Mariottini P, Shah ZH, Toivonen JM, Bagni C, Spelbrink JN, Amaldi F, Jacobs HT
Expression of the gene for mitoribosomal protein S12 is controlled in human cells at the levels of transcription, RNA splicing, and translation.
J Biol Chem 1999 ;274(45)31853-62
PMID

Kajander OA, Poulton J, Spelbrink JN, Rovio A, Karhunen PJ, Jacobs HT
The dangers of extended PCR in the clinic.
Nat Med 1999 ;5(9)965-6
PMID

Lightowlers RN, Jacobs HT, Kajander OA
Mitochondrial DNA--all things bad?
Trends Genet 1999 ;15(3)91-3
PMID

Toivonen JM, Boocock MR, Jacobs HT
Modelling in Escherichia coli of mutations in mitoribosomal protein S12: novel mutant phenotypes of rpsL.
Mol Microbiol 1999 ;31(6)1735-46
PMID

Roberti M, Polosa PL, Musicco C, Milella F, Qureshi SA, Gadaleta MN, Jacobs HT, Cantatore P
In vivo mitochondrial DNA-protein interactions in sea urchin eggs and embryos.
Curr Genet 1999 ;34(6)449-58
PMID

Kajander OA, Kunnas TA, Perola M, Lehtinen SK, Karhunen PJ, Jacobs HT
Long-extension PCR to detect deleted mitochondrial DNA molecules is compromized by technical artefacts.
Biochem Biophys Res Commun 1999 ;254(2)507-14
PMID

Nevanlinna H, Kallioniemi OP
[Susceptibility genes of familial breast cancer in Finland]
Duodecim 1999 ;115(21)2365-74
PMID

Moch H, Schraml P, Bubendorf L, Mirlacher M, Kononen J, Gasser T, Mihatsch MJ, Kallioniemi OP, Sauter G
[Identification of prognostic parameters for renal cell carcinoma by cDNA arrays and cell chips]
Verh Dtsch Ges Pathol 1999 ;83225-32
PMID

Forozan F, Veldman R, Ammerman CA, Parsa NZ, Kallioniemi A, Kallioniemi OP, Ethier SP
Molecular cytogenetic analysis of 11 new breast cancer cell lines.
Br J Cancer 1999 ;81(8)1328-34
PMID

Koivisto PA, Schleutker J, Helin H, Ehren-van Eekelen C, Kallioniemi OP, Trapman J
Androgen receptor gene alterations and chromosomal gains and losses in prostate carcinomas appearing during finasteride treatment for benign prostatic hyperplasia.
Clin Cancer Res 1999 ;5(11)3578-82
PMID

Lee SK, Anzick SL, Choi JE, Bubendorf L, Guan XY, Jung YK, Kallioniemi OP, Kononen J, Trent JM, Azorsa D, Jhun BH, Cheong JH, Lee YC, Meltzer PS, Lee JW
A nuclear factor, ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo.
J Biol Chem 1999 ;274(48)34283-93
PMID

Bubendorf L, Kolmer M, Kononen J, Koivisto P, Mousses S, Chen Y, Mahlamaki E, Schraml P, Moch H, Willi N, Elkahloun AG, Pretlow TG, Gasser TC, Mihatsch MJ, Sauter G, Kallioniemi OP
Hormone therapy failure in human prostate cancer: analysis by complementary DNA and tissue microarrays.
J Natl Cancer Inst 1999 ;91(20)1758-64
PMID

Schraml P, Kononen J, Bubendorf L, Moch H, Bissig H, Nocito A, Mihatsch MJ, Kallioniemi OP, Sauter G
Tissue microarrays for gene amplification surveys in many different tumor types.
Clin Cancer Res 1999 ;5(8)1966-75
PMID

Matikainen MP, Schleutker J, Morsky P, Kallioniemi OP, Tammela TL
Detection of subclinical cancers by prostate-specific antigen screening in asymptomatic men from high-risk prostate cancer families.
Clin Cancer Res 1999 ;5(6)1275-9
PMID

Ingvarsson S, Agnarsson BA, Sigbjornsdottir BI, Kononen J, Kallioniemi OP, Barkardottir RB, Kovatich AJ, Schwarting R, Hauck WW, Huebner K, McCue PA
Reduced Fhit expression in sporadic and BRCA2-linked breast carcinomas.
Cancer Res 1999 ;59(11)2682-9
PMID

Moch H, Schraml P, Bubendorf L, Mirlacher M, Kononen J, Gasser T, Mihatsch MJ, Kallioniemi OP, Sauter G
High-throughput tissue microarray analysis to evaluate genes uncovered by cDNA microarray screening in renal cell carcinoma.
Am J Pathol 1999 ;154(4)981-6
PMID

Desper R, Jiang F, Kallioniemi OP, Moch H, Papadimitriou CH, Schaffer AA
Inferring tree models for oncogenesis from comparative genome hybridization data.
J Comput Biol 1999 ;6(1)37-51
PMID

Bubendorf L, Kononen J, Koivisto P, Schraml P, Moch H, Gasser TC, Willi N, Mihatsch MJ, Sauter G, Kallioniemi OP
Survey of gene amplifications during prostate cancer progression by high-throughout fluorescence in situ hybridization on tissue microarrays.
Cancer Res 1999 ;59(4)803-6
PMID

Kjellman M, Roshani L, Teh BT, Kallioniemi OP, Hoog A, Gray S, Farnebo LO, Holst M, Backdahl M, Larsson C
Genotyping of adrenocortical tumors: very frequent deletions of the MEN1 locus in 11q13 and of a 1-centimorgan region in 2p16.
J Clin Endocrinol Metab 1999 ;84(2)730-5
PMID

Tirkkonen M, Kainu T, Loman N, Johannsson OT, Olsson H, Barkardottir RB, Kallioniemi OP, Borg A
Somatic genetic alterations in BRCA2-associated and sporadic male breast cancer.
Genes Chromosomes Cancer 1999 ;24(1)56-61
PMID

Holzer M, Holzapfel HP, Krohn K, Gertz H-J , Arendt T
Alterations in content and phosphorylation state of cytoskeletal proteins in the sciatic nerve during ageing and in Alzheimer's disease.
J Neural Transm 1999 ;106(7-8)743-55
PMID

Beltran-Valero de Bernabe D, Peterson P, Luopajarvi K, Matintalo P, Alho A, Konttinen Y, Krohn K, Rodriguez de Cordoba S, Ranki A
Mutational analysis of the HGO gene in Finnish alkaptonuria patients.
J Med Genet 1999 ;36(12)922-3
PMID

Bluher M, Krohn K, Wallaschofski H, Braverman LE, Paschke R
Fas and Fas ligand gene expression in autoimmune thyroiditis in BB/W rats.
Eur J Endocrinol 1999 ;141(5)506-11
PMID

Bluher M, Krohn K, Wallaschofski H, Braverman LE, Paschke R
Cytokine gene expression in autoimmune thyroiditis in BioBreeding/Worcester rats.
Thyroid 1999 ;9(10)1049-55
PMID

Ovod VV, Knirel YA, Samson R, Krohn KJ
Immunochemical characterization and taxonomic evaluation of the O polysaccharides of the lipopolysaccharides of Pseudomonas syringae serogroup O1 strains.
J Bacteriol 1999 ;181(22)6937-47
PMID

Collings A, Pitkanen J, Strengell M, Tahtinen M, Lagerstedt A, Hakkarainen K, Ovod V, Sutter G, Ustav M, Ustav E, Mannik A, Ranki A, Peterson P, Krohn K
Humoral and cellular immune responses to HIV-1 nef in mice DNA-immunised with non-replicating or self-replicating expression vectors.
Vaccine 1999 ;18(5-6)460-7
PMID

John M, Krohn K, Florke U, Aust HJ, Draeger S, Schulz B
Biologically active secondary metabolites from fungi. 12.(1) oidiolactones A-F, labdane diterpene derivatives isolated from oidiodendron truncata
J Nat Prod 1999 ;62(9)1218-21
PMID

Grusch M, Rosenberger G, Fuhrmann G, Braun K, Titscher B, Szekeres T, Fritzer-Skekeres M, Oberhuber G, Krohn K, Hengstschlaeger M, Krupitza G, Jayaram HN
Benzamide riboside induces apoptosis independent of Cdc25A expression in human ovarian carcinoma N.1 cells.
Cell Death Differ 1999 ;6(8)736-44
PMID

Trulzsch B, Krohn K, Wonerow P, Paschke R
DGGE is more sensitive for the detection of somatic point mutations than direct sequencing.
Biotechniques 1999 ;27(2)266-8
PMID

Zdorovenko EL, Ovod VV, Shashkov AS, Kocharova NA, Knirel YA, Krohn K
Structure of the O-polysaccharide of the lipopolysaccharide of Pseudomonas syringae pv. garcae ICMP 8047.
Biochemistry (Mosc) 1999 ;64(7)765-73
PMID

Young G, Krohn KA, Packer RJ
Prothrombin G20210A mutation in a child with spinal cord infarction.
J Pediatr 1999 ;134(6)777-9
PMID

Krohn K, Biele C, Aust HJ, Draeger S, Schulz B
Herbarulide, a ketodivinyllactone steroid with an unprecedented homo-6-oxaergostane skeleton from the endophytic fungus pleospora herbarum1
J Nat Prod 1999 ;62(4)629-30
PMID

Wolf N, Krohn K, Bieger S, Frodin M, Gammeltoft S, Krieglstein K, Unsicker K
Transforming growth factor-beta, but not ciliary neurotrophic factor, inhibits DNA synthesis of adrenal medullary cells in vitro.
Neuroscience 1999 ;90(2)629-41
PMID

Krohn K, Emmrich P, Ott N, Paschke R
Increased thyroid epithelial cell proliferation in toxic thyroid nodules.
Thyroid 1999 ;9(3)241-6
PMID

Mankoff DA, Shields AF, Link JM, Graham MM, Muzi M, Peterson LM, Eary JF, Krohn KA
Kinetic analysis of 2-[11C]thymidine PET imaging studies: validation studies.
J Nucl Med 1999 ;40(4)614-24
PMID

Heino M, Peterson P, Kudoh J, Nagamine K, Lagerstedt A, Ovod V, Ranki A, Rantala I, Nieminen M, Tuukkanen J, Scott HS, Antonarakis SE, Shimizu N, Krohn K
Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla.
Biochem Biophys Res Commun 1999 ;257(3)821-5
PMID

Krohn K, Rozovsky I, Wals P, Teter B, Anderson CP, Finch CE
Glial fibrillary acidic protein transcription responses to transforming growth factor-beta1 and interleukin-1beta are mediated by a nuclear factor-1-like site in the near-upstream promoter.
J Neurochem 1999 ;72(4)1353-61
PMID

Ackermann F, Krohn K, Windgassen M, Buchfelder M, Fahlbusch R, Paschke R
Acromegaly in a family without a mutation in the menin gene.
Exp Clin Endocrinol Diabetes 1999 ;107(1)93-6
PMID

Mittaz L, Rossier C, Heino M, Peterson P, Krohn KJ, Gos A, Morris MA, Kudoh J, Shimizu N, Antonarakis SE, Scott HS
Isolation and characterization of the mouse Aire gene.
Biochem Biophys Res Commun 1999 ;255(2)483-90
PMID

Krohn K
TGF-beta1-dependent differential expression of a rat homolog for latent TGF-beta binding protein in astrocytes and C6 glioma cells.
Glia 1999 ;25(4)332-42
PMID

Eary JF, Mankoff DA, Spence AM, Berger MS, Olshen A, Link JM, O'Sullivan F, Krohn KA
2-[C-11]thymidine imaging of malignant brain tumors.
Cancer Res 1999 ;59(3)615-21
PMID

Heino M, Scott HS, Chen Q, Peterson P, Maebpaa U, Papasavvas MP, Mittaz L, Barras C, Rossier C, Chrousos GP, Stratakis CA, Nagamine K, Kudoh J, Shimizu N, Maclaren N, Antonarakis SE, Krohn K
Mutation analyses of North American APS-1 patients.
Hum Mutat 1999 ;13(1)69-74
PMID

Renkema GH, Manninen A, Mann DA, Harris M, Saksela K
Identification of the Nef-associated kinase as p21-activated kinase 2.
Curr Biol 1999 ;9(23)1407-10
PMID

Hiipakka M, Poikonen K, Saksela K
SH3 domains with high affinity and engineered ligand specificities targeted to HIV-1 Nef.
J Mol Biol 1999 ;293(5)1097-106
PMID

Biggs TE, Cooke SJ, Barton CH, Harris MP, Saksela K, Mann DA
Induction of activator protein 1 (AP-1) in macrophages by human immunodeficiency virus type-1 NEF is a cell-type-specific response that requires both hck and MAPK signaling events.
J Mol Biol 1999 ;290(1)21-35
PMID

Lehtinen SK, Spelbrink JN, Jacobs HT
Heteroplasmic segregation associated with trisomy-9 in cultured human cells.
Somat Cell Mol Genet 1999 ;25(5-6)263-74
PMID

Mariottini P, Shah ZH, Toivonen JM, Bagni C, Spelbrink JN, Amaldi F, Jacobs HT
Expression of the gene for mitoribosomal protein S12 is controlled in human cells at the levels of transcription, RNA splicing, and translation.
J Biol Chem 1999 ;274(45)31853-62
PMID

Kajander OA, Poulton J, Spelbrink JN, Rovio A, Karhunen PJ, Jacobs HT
The dangers of extended PCR in the clinic.
Nat Med 1999 ;5(9)965-6
PMID

Pan Y, Kytola S, Farnebo F, Wang N, Lui WO, Nupponen N, Isola J, Visakorpi T, Bergerheim US, Larsson C
Characterization of chromosomal abnormalities in prostate cancer cell lines by spectral karyotyping.
Cytogenet Cell Genet 1999 ;87(3-4)225-32
PMID

Holli K, Visakorpi T, Hakama M
Smoking and survival from lung cancer.
Acta Oncol 1999 ;38(8)989-92
PMID

Nupponen NN, Visakorpi T
Assignment of the protein kinase homolog of YAK1 (HIPK3) to human chromosome band 11p13 by in situ hybridization.
Cytogenet Cell Genet 1999 ;87(1-2)102-3
PMID

Wallen MJ, Linja M, Kaartinen K, Schleutker J, Visakorpi T
Androgen receptor gene mutations in hormone-refractory prostate cancer.
J Pathol 1999 ;189(4)559-63
PMID

Palmberg C, Koivisto P, Visakorpi T, Tammela TL
PSA decline is an independent prognostic marker in hormonally treated prostate cancer.
Eur Urol 1999 ;36(3)191-6
PMID

Nupponen NN, Porkka K, Kakkola L, Tanner M, Persson K, Borg A, Isola J, Visakorpi T
Amplification and overexpression of p40 subunit of eukaryotic translation initiation factor 3 in breast and prostate cancer.
Am J Pathol 1999 ;154(6)1777-83
PMID

Nupponen N, Visakorpi T
Molecular biology of progression of prostate cancer.
Eur Urol 1999 ;35(5-6)351-4
PMID

Visakorpi T
Molecular genetics of prostate cancer.
Ann Chir Gynaecol 1999 ;88(1)11-6
PMID

Haapasalo H, Sallinen S, Sallinen P, Helen P, Jaaskelainen J, Salmi TT, Paetau A, Paljarvi L, Visakorpi T, Kalimo H
Clinicopathological correlation of cell proliferation, apoptosis and p53 in cerebellar pilocytic astrocytomas.
Neuropathol Appl Neurobiol 1999 ;25(2)134-42
PMID

Visakorpi T
New pieces to the prostate cancer puzzle.
Nat Med 1999 ;5(3)264-5
PMID

 
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