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IBT julkaisut 2010

NOTE: This list is not exhaustive because it has been collected by an automatic procedure from PubMed. It may also contain publications not related to IMT or Regea authors (authors having the same name). The same publication may also appear more than once in case several research groups have participated in the writing.
Bioinformatics
Mauno Vihinen - Bioinformatics Group
Kohonen-Corish MR, Al-Aama JY, Auerbach AD, Axton M, Barash CI, Bernstein I, Béroud C, Burn J, Cunningham F, Cutting GR, den Dunnen JT, Greenblatt MS, Kaput J, Katz M, Lindblom A, Macrae F, Maglott D, Möslein G, Povey S, Ramesar R, Richards S, Seminara D, Sobrido MJ, Tavtigian S, Taylor G, Vihinen M, Winship I, Cotton RG,
How to catch all those mutations--the report of the third Human Variome Project Meeting, UNESCO Paris, May 2010.
Hum Mutat 2010 ;31(12)1374-81
PMID

Lanzi G, Ferrari S, Vihinen M, Caraffi S, Kutukculer N, Schiaffonati L, Plebani A, Notarangelo LD, Fra AM, Giliani S
Different molecular behavior of CD40 mutants causing hyper-IgM syndrome.
Blood 2010 ;116(26)5867-74
PMID

Khan S, Vihinen M
Performance of protein stability predictors.
Hum Mutat 2010 ;31(6)675-84
PMID

Howard HJ, Horaitis O, Cotton RG, Vihinen M, Dalgleish R, Robinson P, Brookes AJ, Axton M, Hoffmann R, Tuffery-Giraud S
The Human Variome Project (HVP) 2009 Forum "Towards Establishing Standards".
Hum Mutat 2010 ;31(3)366-7
PMID

Jääskeläinen S, Riikonen P, Salakoski T, Vihinen M
Accuracy of protein hydropathy predictions.
Int J Data Min Bioinform 2010 ;4(6)735-54
PMID

Biotechnology
Vesa Hytönen - Protein Dynamics
Markku Kulomaa - Molecular Biotechnology
Huhti L, Blazevic V, Nurminen K, Koho T, Hytönen VP, Vesikari T
A comparison of methods for purification and concentration of norovirus GII-4 capsid virus-like particles.
Arch Virol 2010 ;155(11)1855-8
PMID

Syrjänen L, Tolvanen M, Hilvo M, Olatubosun A, Innocenti A, Scozzafava A, Leppiniemi J, Niederhauser B, Hytönen VP, Gorr TA, Parkkila S, Supuran CT
Characterization of the first beta-class carbonic anhydrase from an arthropod (Drosophila melanogaster) and phylogenetic analysis of beta-class carbonic anhydrases in invertebrates.
BMC Biochem 2010 ;1128
PMID

Cancer Groups
Jorma Isola - Cancer Biology
Anne Kallioniemi - Cancer Genomics
Tapio Visakorpi - Molecular Biology of Prostate Cancer
Johanna Schleutker - Genetic Predisposition to Cancer
Tuominen VJ, Ruotoistenmäki S, Viitanen A, Jumppanen M, Isola J
ImmunoRatio: a publicly available web application for quantitative image analysis of estrogen receptor (ER), progesterone receptor (PR), and Ki-67.
Breast Cancer Res 2010 ;12(4)R56
PMID

Saarilahti K, Bono P, Kajanti M, Bäck L, Leivo I, Joensuu T, Isola J, Mäkitie AA
Phase II prospective trial of gefitinib given concurrently with cisplatin and radiotherapy in patients with locally advanced head and neck cancer.
J Otolaryngol Head Neck Surg 2010 ;39(3)269-76
PMID

Köninki K, Barok M, Tanner M, Staff S, Pitkänen J, Hemmilä P, Ilvesaro J, Isola J
Multiple molecular mechanisms underlying trastuzumab and lapatinib resistance in JIMT-1 breast cancer cells.
Cancer Lett 2010 ;294(2)211-9
PMID

Parkkila S, Lasota J, Fletcher JA, Ou WB, Kivelä AJ, Nuorva K, Parkkila AK, Ollikainen J, Sly WS, Waheed A, Pastorekova S, Pastorek J, Isola J, Miettinen M
Carbonic anhydrase II. A novel biomarker for gastrointestinal stromal tumors.
Mod Pathol 2010 ;23(5)743-50
PMID

Staff S, Isola J, Jumppanen M, Tanner M
Aurora-A gene is frequently amplified in basal-like breast cancer.
Oncol Rep 2010 ;23(2)307-12
PMID

Joensuu G, Joensuu T, Nokisalmi P, Reddy C, Isola J, Ruutu M, Kouri M, Kupelian PA, Collan J, Pesonen S, Hemminki A
A phase I/II trial of gefitinib given concurrently with radiotherapy in patients with nonmetastatic prostate cancer.
Int J Radiat Oncol Biol Phys 2010 ;78(1)42-9
PMID

Tuominen VJ, Isola J
Linking whole-slide microscope images with DICOM by using JPEG2000 interactive protocol.
J Digit Imaging 2010 ;23(4)454-62
PMID

Kallioniemi A
DNA copy number analysis on tissue microarrays.
Methods Mol Biol 2010 ;664127-34
PMID

Wolf M, Korja M, Karhu R, Edgren H, Kilpinen S, Ojala K, Mousses S, Kallioniemi A, Haapasalo H
Array-based gene expression, CGH and tissue data defines a 12q24 gain in neuroblastic tumors with prognostic implication.
BMC Cancer 2010 ;10181
PMID

Alarmo EL, Kallioniemi A
Bone morphogenetic proteins in breast cancer: dual role in tumourigenesis?
Endocr Relat Cancer 2010 ;17(2)R123-39
PMID

Kuuselo R, Simon R, Karhu R, Tennstedt P, Marx AH, Izbicki JR, Yekebas E, Sauter G, Kallioniemi A
19q13 amplification is associated with high grade and stage in pancreatic cancer.
Genes Chromosomes Cancer 2010 ;49(6)569-75
PMID

Ketolainen JM, Alarmo EL, Tuominen VJ, Kallioniemi A
Parallel inhibition of cell growth and induction of cell migration and invasion in breast cancer cells by bone morphogenetic protein 4.
Breast Cancer Res Treat 2010 ;124(2)377-86
PMID

Gu L, Zhu XH, Visakorpi T, Alanen K, Mirtti T, Edmonston TB, Nevalainen MT
Activating mutation (V617F) in the tyrosine kinase JAK2 is absent in locally-confined or castration-resistant prostate cancer.
Anal Cell Pathol (Amst) 2010 ;33(2)55-9
PMID

Pittman AM, Naranjo S, Jalava SE, Twiss P, Ma Y, Olver B, Lloyd A, Vijayakrishnan J, Qureshi M, Broderick P, van Wezel T, Morreau H, Tuupanen S, Aaltonen LA, Alonso ME, Manzanares M, Gavilán A, Visakorpi T, Gómez-Skarmeta JL, Houlston RS
Allelic variation at the 8q23.3 colorectal cancer risk locus functions as a cis-acting regulator of EIF3H.
PLoS Genet 2010 ;6(9)
PMID

Erkkilä T, Lehmusvaara S, Ruusuvuori P, Visakorpi T, Shmulevich I, Lähdesmäki H
Probabilistic analysis of gene expression measurements from heterogeneous tissues.
Bioinformatics 2010 ;26(20)2571-7
PMID

Leinonen KA, Tolonen TT, Bracken H, Stenman UH, Tammela TL, Saramäki OR, Visakorpi T
Association of SPINK1 expression and TMPRSS2:ERG fusion with prognosis in endocrine-treated prostate cancer.
Clin Cancer Res 2010 ;16(10)2845-51
PMID

Suikki HE, Kujala PM, Tammela TL, van Weerden WM, Vessella RL, Visakorpi T
Genetic alterations and changes in expression of histone demethylases in prostate cancer.
Prostate 2010 ;70(8)889-98
PMID

Rauhala HE, Jalava SE, Isotalo J, Bracken H, Lehmusvaara S, Tammela TL, Oja H, Visakorpi T
miR-193b is an epigenetically regulated putative tumor suppressor in prostate cancer.
Int J Cancer 2010 ;127(6)1363-72
PMID

Christensen GB, Baffoe-Bonnie AB, George A, Powell I, Bailey-Wilson JE, Carpten JD, Giles GG, Hopper JL, Severi G, English DR, Foulkes WD, Maehle L, Moller P, Eeles R, Easton D, Badzioch MD, Whittemore AS, Oakley-Girvan I, Hsieh CL, Dimitrov L, Xu J, Stanford JL, Johanneson B, Deutsch K, McIntosh L, Ostrander EA, Wiley KE, Isaacs SD, Walsh PC, Isaacs WB, Thibodeau SN, McDonnell SK, Hebbring S, Schaid DJ, Lange EM, Cooney KA, Tammela TL, Schleutker J, Paiss T, Maier C, Grönberg H, Wiklund F, Emanuelsson M, Farnham JM, Cannon-Albright LA, Camp NJ,
Genome-wide linkage analysis of 1,233 prostate cancer pedigrees from the International Consortium for Prostate Cancer Genetics using novel sumLINK and sumLOD analyses.
Prostate 2010 ;70(7)735-44
PMID

Cellular Biology
Ari-Pekka Huovila - Cell Interactions
Herma Renkema - Biochemistry of Cell Signaling
Kärkkäinen S, van der Linden M, Renkema GH
POSH2 is a RING finger E3 ligase with Rac1 binding activity through a partial CRIB domain.
FEBS Lett 2010 ;584(18)3867-72
PMID

Mitochondrial Genetics
Howy Jacobs - Mitochondrial Gene Expression and Disease Group
Laurie Kaguni - Mitochondrial Biogenesis in Health and Disease
Alberto Sanz - Mitochondrial Gerontology and Age-related Diseases
Hans Spelbrink - Molecular Biology-Mitochondrial DNA maintenance
Hyvärinen AK, Kumanto MK, Marjavaara SK, Jacobs HT
Effects on mitochondrial transcription of manipulating mTERF protein levels in cultured human HEK293 cells.
BMC Mol Biol 2010 ;1172
PMID

Chua YL, Dufour E, Dassa EP, Rustin P, Jacobs HT, Taylor CT, Hagen T
Stabilization of hypoxia-inducible factor-1alpha protein in hypoxia occurs independently of mitochondrial reactive oxygen species production.
J Biol Chem 2010 ;285(41)31277-84
PMID

Jiménez-Menéndez N, Fernández-Millán P, Rubio-Cosials A, Arnan C, Montoya J, Jacobs HT, Bernadó P, Coll M, Usón I, Solà M
Human mitochondrial mTERF wraps around DNA through a left-handed superhelical tandem repeat.
Nat Struct Mol Biol 2010 ;17(7)891-3
PMID

Pohjoismäki JL, Goffart S, Taylor RW, Turnbull DM, Suomalainen A, Jacobs HT, Karhunen PJ
Developmental and pathological changes in the human cardiac muscle mitochondrial DNA organization, replication and copy number.
PLoS One 2010 ;5(5)e10426
PMID

Sanz A, Fernández-Ayala DJ, Stefanatos RK, Jacobs HT
Mitochondrial ROS production correlates with, but does not directly regulate lifespan in Drosophila.
Aging (Albany NY) 2010 ;2(4)200-23
PMID

Sanz A, Soikkeli M, Portero-Otín M, Wilson A, Kemppainen E, McIlroy G, Ellilä S, Kemppainen KK, Tuomela T, Lakanmaa M, Kiviranta E, Stefanatos R, Dufour E, Hutz B, Naudí A, Jové M, Zeb A, Vartiainen S, Matsuno-Yagi A, Yagi T, Rustin P, Pamplona R, Jacobs HT
Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction.
Proc Natl Acad Sci U S A 2010 ;107(20)9105-10
PMID

Pohjoismäki JL, Holmes JB, Wood SR, Yang MY, Yasukawa T, Reyes A, Bailey LJ, Cluett TJ, Goffart S, Willcox S, Rigby RE, Jackson AP, Spelbrink JN, Griffith JD, Crouch RJ, Jacobs HT, Holt IJ
Mammalian mitochondrial DNA replication intermediates are essentially duplex but contain extensive tracts of RNA/DNA hybrid.
J Mol Biol 2010 ;397(5)1144-55
PMID

Fernández-Ayala DJ, Chen S, Kemppainen E, O'Dell KM, Jacobs HT
Gene expression in a Drosophila model of mitochondrial disease.
PLoS One 2010 ;5(1)e8549
PMID

Oliveira MT, Kaguni LS
Functional roles of the N- and C-terminal regions of the human mitochondrial single-stranded DNA-binding protein.
PLoS One 2010 ;5(10)e15379
PMID

Matsushima Y, Goto Y, Kaguni LS
Mitochondrial Lon protease regulates mitochondrial DNA copy number and transcription by selective degradation of mitochondrial transcription factor A (TFAM).
Proc Natl Acad Sci U S A 2010 ;107(43)18410-5
PMID

Makowska-Grzyska MM, Ziebarth TD, Kaguni LS
Physical analysis of recombinant forms of the human mitochondrial DNA helicase.
Methods 2010 ;51(4)411-5
PMID

Ziebarth TD, Gonzalez-Soltero R, Makowska-Grzyska MM, Núñez-Ramírez R, Carazo JM, Kaguni LS
Dynamic effects of cofactors and DNA on the oligomeric state of human mitochondrial DNA helicase.
J Biol Chem 2010 ;285(19)14639-47
PMID

Dallmann HG, Fackelmayer OJ, Tomer G, Chen J, Wiktor-Becker A, Ferrara T, Pope C, Oliveira MT, Burgers PM, Kaguni LS, McHenry CS
Parallel multiplicative target screening against divergent bacterial replicases: identification of specific inhibitors with broad spectrum potential.
Biochemistry 2010 ;49(11)2551-62
PMID

Palin EJ, Lesonen A, Farr CL, Euro L, Suomalainen A, Kaguni LS
Functional analysis of H. sapiens DNA polymerase gamma spacer mutation W748S with and without common variant E1143G.
Biochim Biophys Acta 2010 ;1802(6)545-51
PMID

Oliveira MT, Garesse R, Kaguni LS
Animal models of mitochondrial DNA transactions in disease and ageing.
Exp Gerontol 2010 ;45(7-8)489-502
PMID

Hiona A, Sanz A, Kujoth GC, Pamplona R, Seo AY, Hofer T, Someya S, Miyakawa T, Nakayama C, Samhan-Arias AK, Servais S, Barger JL, Portero-Otín M, Tanokura M, Prolla TA, Leeuwenburgh C
Mitochondrial DNA mutations induce mitochondrial dysfunction, apoptosis and sarcopenia in skeletal muscle of mitochondrial DNA mutator mice.
PLoS One 2010 ;5(7)e11468
PMID

Sanz A, Fernández-Ayala DJ, Stefanatos RK, Jacobs HT
Mitochondrial ROS production correlates with, but does not directly regulate lifespan in Drosophila.
Aging (Albany NY) 2010 ;2(4)200-23
PMID

Sanz A, Soikkeli M, Portero-Otín M, Wilson A, Kemppainen E, McIlroy G, Ellilä S, Kemppainen KK, Tuomela T, Lakanmaa M, Kiviranta E, Stefanatos R, Dufour E, Hutz B, Naudí A, Jové M, Zeb A, Vartiainen S, Matsuno-Yagi A, Yagi T, Rustin P, Pamplona R, Jacobs HT
Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction.
Proc Natl Acad Sci U S A 2010 ;107(20)9105-10
PMID

Sanz A, Stefanatos R, McIlroy G
Production of reactive oxygen species by the mitochondrial electron transport chain in Drosophila melanogaster.
J Bioenerg Biomembr 2010 ;42(2)135-42
PMID

Pohjoismäki JL, Holmes JB, Wood SR, Yang MY, Yasukawa T, Reyes A, Bailey LJ, Cluett TJ, Goffart S, Willcox S, Rigby RE, Jackson AP, Spelbrink JN, Griffith JD, Crouch RJ, Jacobs HT, Holt IJ
Mammalian mitochondrial DNA replication intermediates are essentially duplex but contain extensive tracts of RNA/DNA hybrid.
J Mol Biol 2010 ;397(5)1144-55
PMID

Spelbrink JN
Functional organization of mammalian mitochondrial DNA in nucleoids: history, recent developments, and future challenges.
IUBMB Life 2010 ;62(1)19-32
PMID

Molecular Immunology
Dan Hultmark - Genetic Immunology
Marko Pesu - Immunoregulation
Mika Rämet - Experimental Immunology
Olli Silvennoinen - Molecular Immunology
Valanne S, Myllymäki H, Kallio J, Schmid MR, Kleino A, Murumägi A, Airaksinen L, Kotipelto T, Kaustio M, Ulvila J, Esfahani SS, Engström Y, Silvennoinen O, Hultmark D, Parikka M, Rämet M
Genome-wide RNA interference in Drosophila cells identifies G protein-coupled receptor kinase 2 as a conserved regulator of NF-kappaB signaling.
J Immunol 2010 ;184(11)6188-98
PMID

Pesu M
[T-helper cells--bandleaders of immune response].
Duodecim 2010 ;126(18)2179-87
PMID

Wang JH, Valanne S, Rämet M
Drosophila as a model for antiviral immunity.
World J Biol Chem 2010 ;1(5)151-9
PMID

Hyvärinen J, Parikka M, Sormunen R, Rämet M, Tryggvason K, Kivirikko KI, Myllyharju J, Koivunen P
Deficiency of a transmembrane prolyl 4-hydroxylase in the zebrafish leads to basement membrane defects and compromised kidney function.
J Biol Chem 2010 ;285(53)42023-32
PMID

Rämet M, Hallman M
Surfactant proteins and respiratory syncytial virus.
J Pediatr 2010 ;157(5)866; author reply 866-7
PMID

Kallio J, Myllymäki H, Grönholm J, Armstrong M, Vanha-aho LM, Mäkinen L, Silvennoinen O, Valanne S, Rämet M
Eye transformer is a negative regulator of Drosophila JAK/STAT signaling.
FASEB J 2010 ;24(11)4467-79
PMID

Grönholm J, Ungureanu D, Vanhatupa S, Rämet M, Silvennoinen O
Sumoylation of Drosophila transcription factor STAT92E.
J Innate Immun 2010 ;2(6)618-24
PMID

Löfgren J, Marttila R, Renko M, Rämet M, Hallman M
Toll-like receptor 4 Asp299Gly polymorphism in respiratory syncytial virus epidemics.
Pediatr Pulmonol 2010 ;45(7)687-92
PMID

Valanne S, Myllymäki H, Kallio J, Schmid MR, Kleino A, Murumägi A, Airaksinen L, Kotipelto T, Kaustio M, Ulvila J, Esfahani SS, Engström Y, Silvennoinen O, Hultmark D, Parikka M, Rämet M
Genome-wide RNA interference in Drosophila cells identifies G protein-coupled receptor kinase 2 as a conserved regulator of NF-kappaB signaling.
J Immunol 2010 ;184(11)6188-98
PMID

Gao X, Ge L, Shao J, Su C, Zhao H, Saarikettu J, Yao X, Yao Z, Silvennoinen O, Yang J
Tudor-SN interacts with and co-localizes with G3BP in stress granules under stress conditions.
FEBS Lett 2010 ;584(16)3525-32
PMID

Kallio J, Myllymäki H, Grönholm J, Armstrong M, Vanha-aho LM, Mäkinen L, Silvennoinen O, Valanne S, Rämet M
Eye transformer is a negative regulator of Drosophila JAK/STAT signaling.
FASEB J 2010 ;24(11)4467-79
PMID

Grönholm J, Ungureanu D, Vanhatupa S, Rämet M, Silvennoinen O
Sumoylation of Drosophila transcription factor STAT92E.
J Innate Immun 2010 ;2(6)618-24
PMID

Saarikettu J, Ovod V, Vuoksio M, Grönholm J, Yang J, Silvennoinen O
Monoclonal antibodies against human Tudor-SN.
Hybridoma (Larchmt) 2010 ;29(3)231-6
PMID

Valanne S, Myllymäki H, Kallio J, Schmid MR, Kleino A, Murumägi A, Airaksinen L, Kotipelto T, Kaustio M, Ulvila J, Esfahani SS, Engström Y, Silvennoinen O, Hultmark D, Parikka M, Rämet M
Genome-wide RNA interference in Drosophila cells identifies G protein-coupled receptor kinase 2 as a conserved regulator of NF-kappaB signaling.
J Immunol 2010 ;184(11)6188-98
PMID

Regenerative Medicine
Katriina Aalto-Setälä - Cardiology Group
Susanna Miettinen - Adult Stem Cell Group
Susanna Narkilahti - Neuro Group
Heli Skottman - Ophthalmology Group
Heliö T, Aalto-Setälä K
[Genetic testing in cardiologic diagnostics].
Duodecim 2010 ;126(14)1685-92
PMID

Rajala K, Lindroos B, Hussein SM, Lappalainen RS, Pekkanen-Mattila M, Inzunza J, Rozell B, Miettinen S, Narkilahti S, Kerkelä E, Aalto-Setälä K, Otonkoski T, Suuronen R, Hovatta O, Skottman H
A defined and xeno-free culture method enabling the establishment of clinical-grade human embryonic, induced pluripotent and adipose stem cells.
PLoS One 2010 ;5(4)e10246
PMID

Pekkanen-Mattila M, Chapman H, Kerkelä E, Suuronen R, Skottman H, Koivisto AP, Aalto-Setälä K
Human embryonic stem cell-derived cardiomyocytes: demonstration of a portion of cardiac cells with fairly mature electrical phenotype.
Exp Biol Med (Maywood) 2010 ;235(4)522-30
PMID

Pekkanen-Mattila M, Pelto-Huikko M, Kujala V, Suuronen R, Skottman H, Aalto-Setälä K, Kerkelä E
Spatial and temporal expression pattern of germ layer markers during human embryonic stem cell differentiation in embryoid bodies.
Histochem Cell Biol 2010 ;133(5)595-606
PMID

Khanna-Jain R, Vuorinen A, Sándor GK, Suuronen R, Miettinen S
Vitamin D(3) metabolites induce osteogenic differentiation in human dental pulp and human dental follicle cells.
J Steroid Biochem Mol Biol 2010 ;122(4)133-41
PMID

Khanna-Jain R, Agata H, Vuorinen A, Sándor GK, Suuronen R, Miettinen S
Addition of BMP-2 or BMP-6 to dexamethasone, ascorbic acid, and β-glycerophosphate may not enhance osteogenic differentiation of human periodontal ligament cells.
Growth Factors 2010 ;28(6)437-46
PMID

Rajala K, Lindroos B, Hussein SM, Lappalainen RS, Pekkanen-Mattila M, Inzunza J, Rozell B, Miettinen S, Narkilahti S, Kerkelä E, Aalto-Setälä K, Otonkoski T, Suuronen R, Hovatta O, Skottman H
A defined and xeno-free culture method enabling the establishment of clinical-grade human embryonic, induced pluripotent and adipose stem cells.
PLoS One 2010 ;5(4)e10246
PMID

Lindroos B, Aho KL, Kuokkanen H, Räty S, Huhtala H, Lemponen R, Yli-Harja O, Suuronen R, Miettinen S
Differential gene expression in adipose stem cells cultured in allogeneic human serum versus fetal bovine serum.
Tissue Eng Part A 2010 ;16(7)2281-94
PMID

Haaparanta AM, Haimi S, Ellä V, Hopper N, Miettinen S, Suuronen R, Kellomäki M
Porous polylactide/beta-tricalcium phosphate composite scaffolds for tissue engineering applications.
J Tissue Eng Regen Med 2010 ;4(5)366-73
PMID

Mäenpää K, Ellä V, Mauno J, Kellomäki M, Suuronen R, Ylikomi T, Miettinen S
Use of adipose stem cells and polylactide discs for tissue engineering of the temporomandibular joint disc.
J R Soc Interface 2010 ;7(42)177-88
PMID

Ylä-Outinen L, Heikkilä J, Skottman H, Suuronen R, Aänismaa R, Narkilahti S
Human cell-based micro electrode array platform for studying neurotoxicity.
Front Neuroeng 2010 ;3
PMID

Lappalainen RS, Salomäki M, Ylä-Outinen L, Heikkilä TJ, Hyttinen JA, Pihlajamäki H, Suuronen R, Skottman H, Narkilahti S
Similarly derived and cultured hESC lines show variation in their developmental potential towards neuronal cells in long-term culture.
Regen Med 2010 ;5(5)749-62
PMID

Sundberg M, Skottman H, Suuronen R, Narkilahti S
Production and isolation of NG2+ oligodendrocyte precursors from human embryonic stem cells in defined serum-free medium.
Stem Cell Res 2010 ;5(2)91-103
PMID

Rajala K, Lindroos B, Hussein SM, Lappalainen RS, Pekkanen-Mattila M, Inzunza J, Rozell B, Miettinen S, Narkilahti S, Kerkelä E, Aalto-Setälä K, Otonkoski T, Suuronen R, Hovatta O, Skottman H
A defined and xeno-free culture method enabling the establishment of clinical-grade human embryonic, induced pluripotent and adipose stem cells.
PLoS One 2010 ;5(4)e10246
PMID

Liu Z, Vuohelainen V, Tarkka M, Tenhunen J, Lappalainen RS, Narkilahti S, Paavonen T, Oksala N, Wu Z, Mennander A
Glutamate release predicts ongoing myocardial ischemia of rat hearts.
Scand J Clin Lab Invest 2010 ;70(3)217-24
PMID

Auer S, Lappalainen RS, Skottman H, Suuronen R, Narkilahti S, Vikholm-Lundin I
An antibody surface for selective neuronal cell attachment.
J Neurosci Methods 2010 ;186(1)72-6
PMID

Ylä-Outinen L, Heikkilä J, Skottman H, Suuronen R, Aänismaa R, Narkilahti S
Human cell-based micro electrode array platform for studying neurotoxicity.
Front Neuroeng 2010 ;3
PMID

Lappalainen RS, Salomäki M, Ylä-Outinen L, Heikkilä TJ, Hyttinen JA, Pihlajamäki H, Suuronen R, Skottman H, Narkilahti S
Similarly derived and cultured hESC lines show variation in their developmental potential towards neuronal cells in long-term culture.
Regen Med 2010 ;5(5)749-62
PMID

Sundberg M, Skottman H, Suuronen R, Narkilahti S
Production and isolation of NG2+ oligodendrocyte precursors from human embryonic stem cells in defined serum-free medium.
Stem Cell Res 2010 ;5(2)91-103
PMID

Rajala K, Lindroos B, Hussein SM, Lappalainen RS, Pekkanen-Mattila M, Inzunza J, Rozell B, Miettinen S, Narkilahti S, Kerkelä E, Aalto-Setälä K, Otonkoski T, Suuronen R, Hovatta O, Skottman H
A defined and xeno-free culture method enabling the establishment of clinical-grade human embryonic, induced pluripotent and adipose stem cells.
PLoS One 2010 ;5(4)e10246
PMID

Pekkanen-Mattila M, Chapman H, Kerkelä E, Suuronen R, Skottman H, Koivisto AP, Aalto-Setälä K
Human embryonic stem cell-derived cardiomyocytes: demonstration of a portion of cardiac cells with fairly mature electrical phenotype.
Exp Biol Med (Maywood) 2010 ;235(4)522-30
PMID

Pekkanen-Mattila M, Pelto-Huikko M, Kujala V, Suuronen R, Skottman H, Aalto-Setälä K, Kerkelä E
Spatial and temporal expression pattern of germ layer markers during human embryonic stem cell differentiation in embryoid bodies.
Histochem Cell Biol 2010 ;133(5)595-606
PMID

Skottman H
Derivation and characterization of three new human embryonic stem cell lines in Finland.
In Vitro Cell Dev Biol Anim 2010 ;46(3-4)206-9
PMID

Auer S, Lappalainen RS, Skottman H, Suuronen R, Narkilahti S, Vikholm-Lundin I
An antibody surface for selective neuronal cell attachment.
J Neurosci Methods 2010 ;186(1)72-6
PMID

 
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