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Lääketieteen ja biotieteiden tiedekuntaTampereen yliopisto BioMediTech

Julkaisut 2016



HUOMIO: Tämä luettelo ei ole ehdottoman täydellinen, koska se on koostettu automaattisesti PubMed-tietokannasta. Sama julkaisu voi esiintyä kahteen tai useampaan kertaan, koska aineisto koostetaan tutkimusryhmittäin. Luettelo voi myös sisältää artikkeita, jotka eivät ole BioMediTech:n tutkijoiden kirjoittamia johtuen samannimisistä kirjoittajista.
Biotechnology
Malin Flodström-Tullberg - THERDIAB
Vesa Hytönen - Protein Dynamics
Markku Kulomaa - Molecular Biotechnology
Laitinen OH, Svedin E, Kapell S, Nurminen A, Hytönen VP, Flodström-Tullberg M
Enteroviral proteases: structure, host interactions and pathogenicity.
Rev Med Virol ;26(4)251-67, 2016
PMID

Brauner H, Hall HT, Flodström-Tullberg M, Kärre K, Höglund P, Johansson S
Depletion of IL-2 receptor β-positive cells protects from diabetes in non-obese diabetic mice.
Immunol Cell Biol ;94(2)177-84, 2016
PMID

Domsgen E, Lind K, Kong L, Hühn MH, Rasool O, van Kuppeveld F, Korsgren O, Lahesmaa R, Flodström-Tullberg M
An IFIH1 gene polymorphism associated with risk for autoimmunity regulates canonical antiviral defence pathways in Coxsackievirus infected human pancreatic islets.
Sci Rep ;2016
PMID

Schulte BM, Gielen PR, Kers-Rebel ED, Prosser AC, Lind K, Flodström-Tullberg M, Tack CJ, Elving LD, Adema GJ
Enterovirus Exposure Uniquely Discriminates Type 1 Diabetes Patients with a Homozygous from a Heterozygous Melanoma Differentiation-Associated Protein 5/Interferon Induced with Helicase C Domain 1 A946T Genotype.
Viral Immunol ;29(7)389-97, 2016
PMID

Pincikova T, Svedin E, Domsgen E, Flodström-Tullberg M, Hjelte L
Cystic fibrosis bronchial epithelial cells have impaired ability to activate vitamin D.
Acta Paediatr ;105(7)851-3, 2016
PMID

Lind K, Svedin E, Domsgen E, Kapell S, Laitinen O, Moll M, Flodström-Tullberg M
Coxsackievirus counters the host innate immune response by blocking type III interferon expression.
J Gen Virol ;97(6)1-12, 2016
PMID

Laitinen OH, Svedin E, Kapell S, Nurminen A, Hytönen VP, Flodström-Tullberg M
Enteroviral proteases: structure, host interactions and pathogenicity.
Rev Med Virol ;26(4)251-67, 2016
PMID

von Essen M, Rahikainen R, Oksala N, Raitoharju E, Seppälä I, Mennander A, Sioris T, Kholová I, Klopp N, Illig T, Karhunen PJ, Kähönen M, Lehtimäki T, Hytönen VP
Talin and vinculin are downregulated in atherosclerotic plaque; Tampere Vascular Study.
Atherosclerosis ;2016
PMID

Ciesielski GL, Hytönen VP, Kaguni LS
Biolayer Interferometry: A Novel Method to Elucidate Protein-Protein and Protein-DNA Interactions in the Mitochondrial DNA Replisome.
Methods Mol Biol ;2016
PMID

Tapio K, Leppiniemi J, Shen B, Hytönen VP, Fritzsche W, Toppari JJ
Toward Single Electron Nanoelectronics Using Self-Assembled DNA Structure.
Nano Lett ;16(11)6780-6786, 2016
PMID

Qi L, Jafari N, Li X, Chen Z, Li L, Hytönen VP, Goult BT, Zhan CG, Huang C
Talin2-mediated traction force drives matrix degradation and cell invasion.
J Cell Sci ;129(19)3661-3674, 2016
PMID

Qiu L, Wang W, Zhang A, Zhang N, Lemma T, Ge H, Toppari JJ, Hytönen VP, Wang J
Core-Shell Nanorod Columnar Array Combined with Gold Nanoplate-Nanosphere Assemblies Enable Powerful In Situ SERS Detection of Bacteria.
ACS Appl Mater Interfaces ;8(37)24394-403, 2016
PMID

Hynninen V, Vuori L, Hannula M, Tapio K, Lahtonen K, Isoniemi T, Lehtonen E, Hirsimäki M, Toppari JJ, Valden M, Hytönen VP
Improved antifouling properties and selective biofunctionalization of stainless steel by employing heterobifunctional silane-polyethylene glycol overlayers and avidin-biotin technology.
Sci Rep ;2016
PMID

Haining AW, von Essen M, Attwood SJ, Hytönen VP, Del Río Hernández A
All Subdomains of the Talin Rod Are Mechanically Vulnerable and May Contribute To Cellular Mechanosensing.
ACS Nano ;10(7)6648-58, 2016
PMID

Hytönen VP, Wehrle-Haller B
Mechanosensing in cell-matrix adhesions - Converting tension into chemical signals.
Exp Cell Res ;343(1)35-41, 2016
PMID

Zolfaghari Emameh R, Barker HR, Tolvanen ME, Parkkila S, Hytönen VP
Horizontal transfer of β-carbonic anhydrase genes from prokaryotes to protozoans, insects, and nematodes.
Parasit Vectors ;2016
PMID

Lehtonen SI, Tullila A, Agrawal N, Kukkurainen S, Kähkönen N, Koskinen M, Nevanen TK, Johnson MS, Airenne TT, Kulomaa MS, Riihimäki TA, Hytönen VP
Artificial Avidin-Based Receptors for a Panel of Small Molecules.
ACS Chem Biol ;11(1)211-21, 2016
PMID

Lehtonen SI, Tullila A, Agrawal N, Kukkurainen S, Kähkönen N, Koskinen M, Nevanen TK, Johnson MS, Airenne TT, Kulomaa MS, Riihimäki TA, Hytönen VP
Artificial Avidin-Based Receptors for a Panel of Small Molecules.
ACS Chem Biol ;11(1)211-21, 2016
PMID

Cancer Groups
Jorma Isola - Cancer Biology
Anne Kallioniemi - Cancer Genomics
Daniela Ungureanu - Cancer Signaling

Pasanen A, Tuomi T, Isola J, Staff S, Bützow R, Loukovaara M
L1 Cell Adhesion Molecule as a Predictor of Disease-Specific Survival and Patterns of Relapse in Endometrial Cancer.
Int J Gynecol Cancer ;26(8)1465-71, 2016
PMID

She QB, Gruvberger-Saal SK, Maurer M, Chen Y, Jumppanen M, Su T, Dendy M, Lau YK, Memeo L, Horlings HM, van de Vijver MJ, Isola J, Hibshoosh H, Rosen N, Parsons R, Saal LH
Integrated molecular pathway analysis informs a synergistic combination therapy targeting PTEN/PI3K and EGFR pathways for basal-like breast cancer.
BMC Cancer ;2016
PMID

Wirtz RM, Sihto H, Isola J, Heikkilä P, Kellokumpu-Lehtinen PL, Auvinen P, Turpeenniemi-Hujanen T, Jyrkkiö S, Lakis S, Schlombs K, Laible M, Weber S, Eidt S, Sahin U, Joensuu H
Biological subtyping of early breast cancer: a study comparing RT-qPCR with immunohistochemistry.
Breast Cancer Res Treat ;157(3)437-46, 2016
PMID

Luhtala S, Staff S, Barok M, Tanner M, Isola J
Comparison of Antibodies for Immunohistochemistry-based Detection of HER3 in Breast Cancer.
Appl Immunohistochem Mol Morphol ;2016
PMID

Luhtala S, Staff S, Tanner M, Isola J
Cyclin E amplification, over-expression, and relapse-free survival in HER-2-positive primary breast cancer.
Tumour Biol ;37(7)9813-23, 2016
PMID

Helin HO, Tuominen VJ, Ylinen O, Helin HJ, Isola J
Free digital image analysis software helps to resolve equivocal scores in HER2 immunohistochemistry.
Virchows Arch ;468(2)191-8, 2016
PMID

Kiiski JI, Fagerholm R, Tervasmäki A, Pelttari LM, Khan S, Jamshidi M, Mantere T, Pylkäs K, Bartek J, Bartkova J, Mannermaa A, Tengström M, Kosma VM, Winqvist R, Kallioniemi A, Aittomäki K, Blomqvist C, Nevanlinna H
FANCM c.5101C>T mutation associates with breast cancer survival and treatment outcome.
Int J Cancer ;139(12)2760-2770, 2016
PMID

Alarmo EL, Havunen R, Häyrynen S, Penkki S, Ketolainen J, Nykter M, Kallioniemi A
Bone morphogenetic protein 4 regulates microRNA expression in breast cancer cell lines in diverse fashion.
Genes Chromosomes Cancer ;55(3)227-36, 2016
PMID

Tomescu DR, Olimpia Dima S, Ungureanu D, Popescu M, Tulbure D, Popescu I
First report of cytokine removal using CytoSorb® in severe noninfectious inflammatory syndrome after liver transplantation.
Int J Artif Organs ;39(3)136-40, 2016
PMID

Tomescu D, Popescu M, Jipa L, Fota R, Ungureanu D, Zamfir R, Orban C, Dima SO, Popescu I
The impact of donor liver graft quality on postoperative outcome in liver transplant recipients. A single centre experience.
Rom J Anaesth Intensive Care ;23(1)19-26, 2016
PMID

Prostate Cancer Research Center (PCRC)

Joentausta RM, Kujala PM, Visakorpi T, Tammela TL, Murtola TJ
Tumor features and survival after radical prostatectomy among antidiabetic drug users.
Prostate Cancer Prostatic Dis ;19(4)367-373, 2016
PMID

Ceder Y, Bjartell A, Culig Z, Rubin MA, Tomlins S, Visakorpi T
The Molecular Evolution of Castration-resistant Prostate Cancer.
Eur Urol Focus ;2(5)506-513, 2016
PMID

Rane JK, Erb HH, Nappo G, Mann VM, Simms MS, Collins AT, Visakorpi T, Maitland NJ
Inhibition of the glucocorticoid receptor results in an enhanced miR-99a/100-mediated radiation response in stem-like cells from human prostate cancers.
Oncotarget ;7(32)51965-51980, 2016
PMID

Nurminen R, Rantapero T, Wong SC, Fischer D, Lehtonen R, Tammela TL, Nykter M, Visakorpi T, Wahlfors T, Schleutker J
Expressional profiling of prostate cancer risk SNPs at 11q13.5 identifies DGAT2 as a new target gene.
Genes Chromosomes Cancer ;55(8)661-73, 2016
PMID

Latonen L, Leinonen KA, Grönlund T, Vessella RL, Tammela TL, Saramäki OR, Visakorpi T
Amplification of the 9p13.3 chromosomal region in prostate cancer.
Genes Chromosomes Cancer ;55(8)617-25, 2016
PMID

Fabris L, Ceder Y, Chinnaiyan AM, Jenster GW, Sorensen KD, Tomlins S, Visakorpi T, Calin GA
The Potential of MicroRNAs as Prostate Cancer Biomarkers.
Eur Urol ;70(2)312-22, 2016
PMID

Haldrup C, Lynnerup AS, Storebjerg TM, Vang S, Wild P, Visakorpi T, Arsov C, Schulz WA, Lindberg J, Grönberg H, Egevad L, Borre M, Ørntoft TF, Høyer S, Sørensen KD
Large-scale evaluation of SLC18A2 in prostate cancer reveals diagnostic and prognostic biomarker potential at three molecular levels.
Mol Oncol ;10(6)825-37, 2016
PMID

Bova GS, Kallio HM, Annala M, Kivinummi K, Högnäs G, Häyrynen S, Rantapero T, Kivinen V, Isaacs WB, Tolonen T, Nykter M, Visakorpi T
Integrated clinical, whole-genome, and transcriptome analysis of multisampled lethal metastatic prostate cancer.
Cold Spring Harb Mol Case Stud ;2(3)a000752, 2016
PMID

Routila J, Bilgen T, Saramäki O, Grénman R, Visakorpi T, Westermarck J, Ventelä S
Copy number increase of oncoprotein CIP2A is associated with poor patient survival in human head and neck squamous cell carcinoma.
J Oral Pathol Med ;45(5)329-37, 2016
PMID

Olvedy M, Scaravilli M, Hoogstrate Y, Visakorpi T, Jenster G, Martens-Uzunova ES
A comprehensive repertoire of tRNA-derived fragments in prostate cancer.
Oncotarget ;7(17)24766-77, 2016
PMID

Keskiväli T, Kujala P, Visakorpi T, Tammela TL, Murtola TJ
Statin use and risk of disease recurrence and death after radical prostatectomy.
Prostate ;76(5)469-78, 2016
PMID

Sjöblom L, Saramäki O, Annala M, Leinonen K, Nättinen J, Tolonen T, Wahlfors T, Nykter M, Bova GS, Schleutker J, Tammela TL, Lilja H, Visakorpi T
Microseminoprotein-Beta Expression in Different Stages of Prostate Cancer.
PLoS One ;11(3)e0150241, 2016
PMID

Ruusuvuori P, Valkonen M, Nykter M, Visakorpi T, Latonen L
Feature-based analysis of mouse prostatic intraepithelial neoplasia in histological tissue sections.
J Pathol Inform ;2016
PMID

Latonen L, Kujala P, Visakorpi T
Incidence of Mucinous Metaplasia in the Prostate of FVB/N Mice (Mus musculus).
Comp Med ;66(4)286-9, 2016
PMID

Scaravilli M, Kivinummi K, Visakorpi T, Latonen L
Measuring the Expression of microRNAs Regulated by Androgens.
Methods Mol Biol ;2016
PMID

Kämpjärvi K, Kim NH, Keskitalo S, Clark AD, von Nandelstadh P, Turunen M, Heikkinen T, Park MJ, Mäkinen N, Kivinummi K, Lintula S, Hotakainen K, Nevanlinna H, Hokland P, Böhling T, Bützow R, Böhm J, Mecklin JP, Järvinen H, Kontro M, Visakorpi T, Taipale J, Varjosalo M, Boyer TG, Vahteristo P
Somatic MED12 mutations in prostate cancer and uterine leiomyomas promote tumorigenesis through distinct mechanisms.
Prostate ;76(1)22-31, 2016
PMID

Neal D, Lilja H
Circulating Tumor Cell Count as an Indicator of Treatment Benefit in Advanced Prostate Cancer.
Eur Urol ;70(6)993-994, 2016
PMID

Carlsson SV, de Carvalho TM, Roobol MJ, Hugosson J, Auvinen A, Kwiatkowski M, Villers A, Zappa M, Nelen V, Páez A, Eastham JA, Lilja H, de Koning HJ, Vickers AJ, Heijnsdijk EA
Estimating the harms and benefits of prostate cancer screening as used in common practice versus recommended good practice: A microsimulation screening analysis.
Cancer ;122(21)3386-3393, 2016
PMID

Vickers A, Vertosick EA, Sjoberg DD, Roobol MJ, Hamdy F, Neal D, Bjartell A, Hugosson J, Donovan JL, Villers A, Zappala S, Lilja H
Properties of the 4-Kallikrein Panel Outside the Diagnostic Gray Zone: Meta-Analysis of Patients with Positive Digital Rectal Examination or Prostate Specific Antigen 10 ng/ml and Above.
J Urol ;2016
PMID

Vickers AJ, Eastham JA, Scardino PT, Lilja H
Reply to Re: The Memorial Sloan Kettering Cancer Center Recommendations for Prostate Cancer Screening.
Urology ;2016
PMID

Thorek DL, Watson PA, Lee SG, Ku AT, Bournazos S, Braun K, Kim K, Sjöström K, Doran MG, Lamminmäki U, Santos E, Veach D, Turkekul M, Casey E, Lewis JS, Abou DS, van Voss MR, Scardino PT, Strand SE, Alpaugh ML, Scher HI, Lilja H, Larson SM, Ulmert D
Internalization of secreted antigen-targeted antibodies by the neonatal Fc receptor for precision imaging of the androgen receptor axis.
Sci Transl Med ;8(367)367ra167, 2016
PMID

Kim EH, Andriole GL, Crawford ED, Sjoberg DD, Assel M, Vickers AJ, Lilja H
Detection of High-Grade Prostate Cancer among PLCO Participants Using a Prespecified Four Kallikrein Marker Panel.
J Urol ;2016
PMID

Loeb S, Lilja H, Vickers A
Beyond prostate-specific antigen: utilizing novel strategies to screen men for prostate cancer.
Curr Opin Urol ;26(5)459-65, 2016
PMID

Krzyzanowska A, Lippolis G, Helczynski L, Anand A, Peltola M, Pettersson K, Lilja H, Bjartell A
Quantitative Time-Resolved Fluorescence Imaging of Androgen Receptor and Prostate-Specific Antigen in Prostate Tissue Sections.
J Histochem Cytochem ;64(5)311-22, 2016
PMID

Sjöblom L, Saramäki O, Annala M, Leinonen K, Nättinen J, Tolonen T, Wahlfors T, Nykter M, Bova GS, Schleutker J, Tammela TL, Lilja H, Visakorpi T
Microseminoprotein-Beta Expression in Different Stages of Prostate Cancer.
PLoS One ;11(3)e0150241, 2016
PMID

Vickers AJ, Eastham JA, Scardino PT, Lilja H
Author Reply.
Urology ;2016
PMID

Vickers AJ, Eastham JA, Scardino PT, Lilja H
The Memorial Sloan Kettering Cancer Center Recommendations for Prostate Cancer Screening.
Urology ;2016
PMID

Verrill C, Cerundolo L, Mckee C, White M, Kartsonaki C, Fryer E, Morris E, Brewster S, Ratnayaka I, Marsden L, Lilja H, Muschel R, Lu X, Hamdy F, Bryant RJ
Altered expression of epithelial-to-mesenchymal transition proteins in extraprostatic prostate cancer.
Oncotarget ;7(2)1107-19, 2016
PMID

Braun K, Sjoberg DD, Vickers AJ, Lilja H, Bjartell AS
A Four-kallikrein Panel Predicts High-grade Cancer on Biopsy: Independent Validation in a Community Cohort.
Eur Urol ;69(3)505-11, 2016
PMID

Bova GS, Kallio HM, Annala M, Kivinummi K, Högnäs G, Häyrynen S, Rantapero T, Kivinen V, Isaacs WB, Tolonen T, Nykter M, Visakorpi T
Integrated clinical, whole-genome, and transcriptome analysis of multisampled lethal metastatic prostate cancer.
Cold Spring Harb Mol Case Stud ;2(3)a000752, 2016
PMID

Myneni S, Patel VL, Bova GS, Wang J, Ackerman CF, Berlinicke CA, Chen SH, Lindvall M, Zack DJ
Resolving complex research data management issues in biomedical laboratories: Qualitative study of an industry-academia collaboration.
Comput Methods Programs Biomed ;2016
PMID

Sjöblom L, Saramäki O, Annala M, Leinonen K, Nättinen J, Tolonen T, Wahlfors T, Nykter M, Bova GS, Schleutker J, Tammela TL, Lilja H, Visakorpi T
Microseminoprotein-Beta Expression in Different Stages of Prostate Cancer.
PLoS One ;11(3)e0150241, 2016
PMID

Computational Biology
Matti Nykter - Computational Biology
Ulman V, Svoboda D, Nykter M, Kozubek M, Ruusuvuori P
Virtual cell imaging: A review on simulation methods employed in image cytometry.
Cytometry A ;89(12)1057-1072, 2016
PMID

Wyatt AW, Azad AA, Volik SV, Annala M, Beja K, McConeghy B, Haegert A, Warner EW, Mo F, Brahmbhatt S, Shukin R, Le Bihan S, Gleave ME, Nykter M, Collins CC, Chi KN
Genomic Alterations in Cell-Free DNA and Enzalutamide Resistance in Castration-Resistant Prostate Cancer.
JAMA Oncol ;2(12)1598-1606, 2016
PMID

Teppo S, Laukkanen S, Liuksiala T, Nordlund J, Oittinen M, Teittinen K, Grönroos T, St-Onge P, Sinnett D, Syvänen AC, Nykter M, Viiri K, Heinäniemi M, Lohi O
Genome-wide repression of eRNA and target gene loci by the ETV6-RUNX1 fusion in acute leukemia.
Genome Res ;26(11)1468-1477, 2016
PMID

Cordova ZM, Grönholm A, Kytölä V, Taverniti V, Hämäläinen S, Aittomäki S, Niininen W, Junttila I, Ylipää A, Nykter M, Pesu M
Myeloid cell expressed proprotein convertase FURIN attenuates inflammation.
Oncotarget ;7(34)54392-54404, 2016
PMID

Nurminen R, Rantapero T, Wong SC, Fischer D, Lehtonen R, Tammela TL, Nykter M, Visakorpi T, Wahlfors T, Schleutker J
Expressional profiling of prostate cancer risk SNPs at 11q13.5 identifies DGAT2 as a new target gene.
Genes Chromosomes Cancer ;55(8)661-73, 2016
PMID

Bova GS, Kallio HM, Annala M, Kivinummi K, Högnäs G, Häyrynen S, Rantapero T, Kivinen V, Isaacs WB, Tolonen T, Nykter M, Visakorpi T
Integrated clinical, whole-genome, and transcriptome analysis of multisampled lethal metastatic prostate cancer.
Cold Spring Harb Mol Case Stud ;2(3)a000752, 2016
PMID

Sjöblom L, Saramäki O, Annala M, Leinonen K, Nättinen J, Tolonen T, Wahlfors T, Nykter M, Bova GS, Schleutker J, Tammela TL, Lilja H, Visakorpi T
Microseminoprotein-Beta Expression in Different Stages of Prostate Cancer.
PLoS One ;11(3)e0150241, 2016
PMID

Alarmo EL, Havunen R, Häyrynen S, Penkki S, Ketolainen J, Nykter M, Kallioniemi A
Bone morphogenetic protein 4 regulates microRNA expression in breast cancer cell lines in diverse fashion.
Genes Chromosomes Cancer ;55(3)227-36, 2016
PMID

Määttä K, Rantapero T, Lindström A, Nykter M, Kankuri-Tammilehto M, Laasanen SL, Schleutker J
Whole-exome sequencing of Finnish hereditary breast cancer families.
Eur J Hum Genet ;25(1)85-93, 2016
PMID

Ruusuvuori P, Valkonen M, Nykter M, Visakorpi T, Latonen L
Feature-based analysis of mouse prostatic intraepithelial neoplasia in histological tissue sections.
J Pathol Inform ;2016
PMID

Mitochondrial Genetics
Howy Jacobs - Mitochondrial Gene Expression and Disease Group
Laurie Kaguni - Mitochondrial Biogenesis in Health and Disease
Mills EL, Kelly B, Logan A, Costa ASH, Varma M, Bryant CE, Tourlomousis P, Däbritz JHM, Gottlieb E, Latorre I, Corr SC, McManus G, Ryan D, Jacobs HT, Szibor M, Xavier RJ, Braun T, Frezza C, Murphy MP, O'Neill LA
Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages.
Cell ;167(2)457-470.e13, 2016
PMID

Andjelković A, Kemppainen KK, Jacobs HT
Ligand-Bound GeneSwitch Causes Developmental Aberrations in Drosophila that Are Alleviated by the Alternative Oxidase.
G3 (Bethesda) ;6(9)2839-46, 2016
PMID

Shi Y, Posse V, Zhu X, Hyvärinen AK, Jacobs HT, Falkenberg M, Gustafsson CM
Mitochondrial transcription termination factor 1 directs polar replication fork pausing.
Nucleic Acids Res ;44(12)5732-42, 2016
PMID

El-Khoury R, Kaulio E, Lassila KA, Crowther DC, Jacobs HT, Rustin P
Expression of the alternative oxidase mitigates beta-amyloid production and toxicity in model systems.
Free Radic Biol Med ;2016
PMID

Kemppainen E, George J, Garipler G, Tuomela T, Kiviranta E, Soga T, Dunn CD, Jacobs HT
Correction: Mitochondrial Dysfunction Plus High-Sugar Diet Provokes a Metabolic Crisis That Inhibits Growth.
PLoS One ;11(3)e0151421, 2016
PMID

Kemppainen E, George J, Garipler G, Tuomela T, Kiviranta E, Soga T, Dunn CD, Jacobs HT
Mitochondrial Dysfunction Plus High-Sugar Diet Provokes a Metabolic Crisis That Inhibits Growth.
PLoS One ;11(1)e0145836, 2016
PMID

Stiban J, So M, Kaguni LS
Iron-Sulfur Clusters in Mitochondrial Metabolism: Multifaceted Roles of a Simple Cofactor.
Biochemistry (Mosc) ;81(10)1066-1080, 2016
PMID

Kaguni LS, Oliveira MT
Structure, function and evolution of the animal mitochondrial replicative DNA helicase.
Crit Rev Biochem Mol Biol ;51(1)53-64, 2016
PMID

Ciesielski GL, Rosado-Ruiz FA, Kaguni LS
Purification and Comparative Assay of Human Mitochondrial Single-Stranded DNA-Binding Protein.
Methods Mol Biol ;2016
PMID

Rosado-Ruiz FA, So M, Kaguni LS
Purification and Comparative Assay of the Human Mitochondrial Replicative DNA Helicase.
Methods Mol Biol ;2016
PMID

Kaguni LS, Oliveira MT, Tamanoi F
Preface.
Enzymes ;2016
PMID

Ciesielski GL, Oliveira MT, Kaguni LS
Animal Mitochondrial DNA Replication.
Enzymes ;2016
PMID

Ciesielski GL, Hytönen VP, Kaguni LS
Biolayer Interferometry: A Novel Method to Elucidate Protein-Protein and Protein-DNA Interactions in the Mitochondrial DNA Replisome.
Methods Mol Biol ;2016
PMID

Gajewski JP, Arnold JJ, Salminen TS, Kaguni LS, Cameron CE
Expression and Purification of Mitochondrial RNA Polymerase and Transcription Factor A from Drosophila melanogaster.
Methods Mol Biol ;2016
PMID

Molecular Immunology
Dan Hultmark - Genetic Immunology
Marko Pesu - Immunoregulation
Mika Rämet - Experimental Immunology
Sadanandan SA, Ekström JO, Jonna VR, Hofer A, Hultmark D
VP3 is crucial for the stability of Nora virus virions.
Virus Res ;2016
PMID

Schmid MR, Anderl I, Vo HT, Valanne S, Yang H, Kronhamn J, Rämet M, Rusten TE, Hultmark D
Genetic Screen in Drosophila Larvae Links ird1 Function to Toll Signaling in the Fat Body and Hemocyte Motility.
PLoS One ;11(7)e0159473, 2016
PMID

Anderl I, Vesala L, Ihalainen TO, Vanha-Aho LM, Andó I, Rämet M, Hultmark D
Transdifferentiation and Proliferation in Two Distinct Hemocyte Lineages in Drosophila melanogaster Larvae after Wasp Infection.
PLoS Pathog ;12(7)e1005746, 2016
PMID

Yang H, Hultmark D
Tissue communication in a systemic immune response of Drosophila.
Fly (Austin) ;10(3)115-22, 2016
PMID

Ekström JO, Hultmark D
A Novel Strategy for Live Detection of Viral Infection in Drosophila melanogaster.
Sci Rep ;2016
PMID

Vähätupa M, Aittomäki S, Martinez Cordova Z, May U, Prince S, Uusitalo-Järvinen H, Järvinen TA, Pesu M
T-cell-expressed proprotein convertase FURIN inhibits DMBA/TPA-induced skin cancer development.
Oncoimmunology ;5(12)e1245266, 2016
PMID

Cordova ZM, Grönholm A, Kytölä V, Taverniti V, Hämäläinen S, Aittomäki S, Niininen W, Junttila I, Ylipää A, Nykter M, Pesu M
Myeloid cell expressed proprotein convertase FURIN attenuates inflammation.
Oncotarget ;7(34)54392-54404, 2016
PMID

Paukkeri EL, Korhonen R, Hämäläinen M, Pesu M, Eskelinen A, Moilanen T, Moilanen E
The Inflammatory Phenotype in Failed Metal-On-Metal Hip Arthroplasty Correlates with Blood Metal Concentrations.
PLoS One ;11(5)e0155121, 2016
PMID

Grönholm A, Junttila I, Pesu M
[Innate lymphoid cells - a new group of immune cells].
Duodecim ;132(9)820-7, 2016
PMID

Pesu M
New insights into the host cell necrosis in tuberculosis.
Virulence ;7(1)1-2, 2016
PMID

Salminen TS, Rämet M
Pickle Flavors Relish in Drosophila Immunity.
Cell Host Microbe ;20(3)273-274, 2016
PMID

Schmid MR, Anderl I, Vo HT, Valanne S, Yang H, Kronhamn J, Rämet M, Rusten TE, Hultmark D
Genetic Screen in Drosophila Larvae Links ird1 Function to Toll Signaling in the Fat Body and Hemocyte Motility.
PLoS One ;11(7)e0159473, 2016
PMID

Myllymäki H, Bäuerlein CA, Rämet M
The Zebrafish Breathes New Life into the Study of Tuberculosis.
Front Immunol ;2016
PMID

Anderl I, Vesala L, Ihalainen TO, Vanha-Aho LM, Andó I, Rämet M, Hultmark D
Transdifferentiation and Proliferation in Two Distinct Hemocyte Lineages in Drosophila melanogaster Larvae after Wasp Infection.
PLoS Pathog ;12(7)e1005746, 2016
PMID

Vanha-Aho LM, Valanne S, Rämet M
Cytokines in Drosophila immunity.
Immunol Lett ;2016
PMID

Utriainen M, Rämet M
[Immuno-oncology--silver bullets or mass destruction weapons?].
Duodecim ;132(8)721-8, 2016
PMID

Oksanen KE, Myllymäki H, Ahava MJ, Mäkinen L, Parikka M, Rämet M
DNA vaccination boosts Bacillus Calmette-Guérin protection against mycobacterial infection in zebrafish.
Dev Comp Immunol ;54(1)89-96, 2016
PMID

Regenerative Medicine
Katriina Aalto-Setälä - Cardiology Group
Susanna Miettinen - Adult Stem Cell Group
Susanna Narkilahti - Neuro Group
Heli Skottman - Eye Group
Kuusela J, Kim J, Räsänen E, Aalto-Setälä K
The Effects of Pharmacological Compounds on Beat Rate Variations in Human Long QT-Syndrome Cardiomyocytes.
Stem Cell Rev ;12(6)698-707, 2016
PMID

Laurila E, Ahola A, Hyttinen J, Aalto-Setälä K
Methods for in vitro functional analysis of iPSC derived cardiomyocytes - Special focus on analyzing the mechanical beating behavior.
Biochim Biophys Acta ;1863(7 Pt B)1864-72, 2016
PMID

Paavola J, Väänänen H, Larsson K, Penttinen K, Toivonen L, Kontula K, Laine M, Aalto-Setälä K, Swan H, Viitasalo M
Slowed depolarization and irregular repolarization in catecholaminergic polymorphic ventricular tachycardia: a study from cellular Ca2+ transients and action potentials to clinical monophasic action potentials and electrocardiography.
Europace ;18(10)1599-1607, 2016
PMID

Joutsijoki H, Haponen M, Rasku J, Aalto-Setälä K, Juhola M
Machine Learning Approach to Automated Quality Identification of Human Induced Pluripotent Stem Cell Colony Images.
Comput Math Methods Med ;2016
PMID

Kuusela J, Kujala VJ, Kiviaho A, Ojala M, Swan H, Kontula K, Aalto-Setälä K
Effects of cardioactive drugs on human induced pluripotent stem cell derived long QT syndrome cardiomyocytes.
Springerplus ;2016
PMID

Joutsijoki H, Haponen M, Rasku J, Aalto-Setälä K, Juhola M
Error-Correcting Output Codes in Classification of Human Induced Pluripotent Stem Cell Colony Images.
Biomed Res Int ;2016
PMID

Ojala M, Prajapati C, Pölönen RP, Rajala K, Pekkanen-Mattila M, Rasku J, Larsson K, Aalto-Setälä K
Mutation-Specific Phenotypes in hiPSC-Derived Cardiomyocytes Carrying Either Myosin-Binding Protein C Or α-Tropomyosin Mutation for Hypertrophic Cardiomyopathy.
Stem Cells Int ;2016
PMID

Sayyar S, Bjorninen M, Haimi S, Miettinen S, Gilmore K, Grijpma D, Wallace G
UV Cross-Linkable Graphene/Poly(trimethylene Carbonate) Composites for 3D Printing of Electrically Conductive Scaffolds.
ACS Appl Mater Interfaces ;8(46)31916-31925, 2016
PMID

Blanquer SB, Gebraad AW, Miettinen S, Poot AA, Grijpma DW, Haimi SP
Differentiation of adipose stem cells seeded towards annulus fibrosus cells on a designed poly(trimethylene carbonate) scaffold prepared by stereolithography.
J Tissue Eng Regen Med ;2016
PMID

Kattipparambil Rajan D, Patrikoski M, Verho J, Sivula J, Ihalainen H, Miettinen S, Lekkala J
Optical non-contact pH measurement in cell culture with sterilizable, modular parts.
Talanta ;2016
PMID

Lappalainen OP, Karhula S, Haapea M, Kyllönen L, Haimi S, Miettinen S, Saarakkala S, Korpi J, Ylikontiola LP, Serlo WS, Sándor GK
Bone healing in rabbit calvarial critical-sized defects filled with stem cells and growth factors combined with granular or solid scaffolds.
Childs Nerv Syst ;32(4)681-8, 2016
PMID

Vuornos K, Björninen M, Talvitie E, Paakinaho K, Kellomäki M, Huhtala H, Miettinen S, Seppänen-Kaijansinkko R, Haimi S
Human Adipose Stem Cells Differentiated on Braided Polylactide Scaffolds Is a Potential Approach for Tendon Tissue Engineering.
Tissue Eng Part A ;22(5-6)513-23, 2016
PMID

Lenk K, Priwitzer B, Ylä-Outinen L, Tietz LH, Narkilahti S, Hyttinen JA
Simulation of developing human neuronal cell networks.
Biomed Eng Online ;15(1)105, 2016
PMID

Kiiski H, Tenhunen J, Ala-Peijari M, Huhtala H, Hämäläinen M, Långsjö J, Moilanen E, Narkilahti S, Öhman J, Peltola J
Increased plasma UCH-L1 after aneurysmal subarachnoid hemorrhage is associated with unfavorable neurological outcome.
J Neurol Sci ;2016
PMID

Kapucu FE, Mäkinen ME, Tanskanen JMA, Ylä-Outinen L, Narkilahti S, Hyttinen JAK
Joint analysis of extracellular spike waveforms and neuronal network bursts.
J Neurosci Methods ;2016
PMID

Abu Khamidakh AE, Dos Santos FC, Skottman H, Juuti-Uusitalo K, Hyttinen J
Semi-automatic Method for Ca(2+) Imaging Data Analysis of Maturing Human Embryonic Stem Cells-Derived Retinal Pigment Epithelium.
Ann Biomed Eng ;44(11)3408-3420, 2016
PMID

Calejo MT, Ilmarinen T, Jongprasitkul H, Skottman H, Kellomäki M
Honeycomb porous films as permeable scaffold materials for human embryonic stem cell-derived retinal pigment epithelium.
J Biomed Mater Res A ;104(7)1646-56, 2016
PMID

Mikhailova A, Ilmarinen T, Ratnayake A, Petrovski G, Uusitalo H, Skottman H, Rafat M
Human pluripotent stem cell-derived limbal epithelial stem cells on bioengineered matrices for corneal reconstruction.
Exp Eye Res ;2016
PMID

Nanni L, Paci M, dos Santos FL, Skottman H, Juuti-Uusitalo K, Hyttinen J
Texture Descriptors Ensembles Enable Image-Based Classification of Maturation of Human Stem Cell-Derived Retinal Pigmented Epithelium.
PLoS One ;11(2)e0149399, 2016
PMID

 
Ylläpito: webmaster@biomeditech.fi
Muutettu: 12.1.2017 12.57 Muokkaa

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Tampereen yliopisto
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