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university of tampere: faculty of medicine and life sciences:
Lääketieteen ja biotieteiden tiedekuntaTampereen yliopisto BioMediTech

Publications 2017



NOTE: This list is not exhaustive because it has been collected by an automatic procedure from PubMed. It may also contain publications not related to BioMediTech or authors (authors having the same name). The same publication may also appear more than once in case several research groups have participated in the writing.
Biotechnology
Malin Flodström-Tullberg - THERDIAB
Vesa Hytönen - Protein Dynamics
Markku Kulomaa - Molecular Biotechnology
Forkel M, Berglin L, Kekäläinen E, Carlsson A, Svedin E, Michaëlsson J, Nagasawa M, Erjefält JS, Mori M, Flodström-Tullberg M, Bergquist A, Ljunggren HG, Westgren M, Lindforss U, Friberg D, Jorns C, Ellis E, Björkström NK, Mjösberg J
Composition and functionality of the intrahepatic innate lymphoid cell-compartment in human nonfibrotic and fibrotic livers.
Eur J Immunol ;47(8)1280-1294, 2017
PMID

Hankaniemi MM, Laitinen OH, Stone VM, Sioofy-Khojine A, Määttä JAE, Larsson PG, Marjomäki V, Hyöty H, Flodström-Tullberg M, Hytönen VP
Optimized production and purification of Coxsackievirus B1 vaccine and its preclinical evaluation in a mouse model.
Vaccine ;35(30)3718-3725, 2017
PMID

Svedin E, Utorova R, Hühn MH, Larsson P, Stone VM, Garimella M, Lind K, Hägglöf T, Pincikova T, Laitinen O, McInerney GM, Scholte B, Hjelte L, Karlsson MCI, Flodström-Tullberg M
A Link Between a Common Mutation in CFTR and Impaired Innate and Adaptive Viral Defence.
J Infect Dis ;2017
PMID

Edlund A, Pedersen MG, Lindqvist A, Wierup N, Flodström-Tullberg M, Eliasson L
CFTR is involved in the regulation of glucagon secretion in human and rodent alpha cells.
Sci Rep ;7(1)90, 2017
PMID

Hankaniemi MM, Laitinen OH, Stone VM, Sioofy-Khojine A, Määttä JAE, Larsson PG, Marjomäki V, Hyöty H, Flodström-Tullberg M, Hytönen VP
Optimized production and purification of Coxsackievirus B1 vaccine and its preclinical evaluation in a mouse model.
Vaccine ;35(30)3718-3725, 2017
PMID

Agrawal N, Määttä JAE, Kulomaa MS, Hytönen VP, Johnson MS, Airenne TT
Structural characterization of core-bradavidin in complex with biotin.
PLoS One ;12(4)e0176086, 2017
PMID

Kumar M, Rahikainen R, Unruh D, Hytönen VP, Delbrück C, Sindelar R, Renz F
Mixture of PLA-PEG and biotinylated albumin enables immobilization of avidins on electrospun fibers.
J Biomed Mater Res A ;105(2)356-362, 2017
PMID

Hytönen VP
Optimized Streptavidin for Fluorescent Labeling of Biotinylated Targets.
Cell Chem Biol ;24(8)921-922, 2017
PMID

Leppiniemi J, Lahtinen P, Paajanen A, Mahlberg R, Metsä-Kortelainen S, Pinomaa T, Pajari H, Vikholm-Lundin I, Pursula P, Hytönen VP
3D-Printable Bioactivated Nanocellulose-Alginate Hydrogels.
ACS Appl Mater Interfaces ;9(26)21959-21970, 2017
PMID

Rahikainen R, von Essen M, Schaefer M, Qi L, Azizi L, Kelly C, Ihalainen TO, Wehrle-Haller B, Bastmeyer M, Huang C, Hytönen VP
Mechanical stability of talin rod controls cell migration and substrate sensing.
Sci Rep ;7(1)3571, 2017
PMID

Oksala NKJ, Seppälä I, Rahikainen R, Mäkelä KM, Raitoharju E, Illig T, Klopp N, Kholova I, Laaksonen R, Karhunen PJ, Hytönen VP, Lehtimäki T
Synergistic Expression of Histone Deacetylase 9 and Matrix Metalloproteinase 12 in M4 Macrophages in Advanced Carotid Plaques.
Eur J Vasc Endovasc Surg ;53(5)632-640, 2017
PMID

Yuan Y, Li L, Zhu Y, Qi L, Azizi L, Hytönen VP, Zhan CG, Huang C
The molecular basis of talin2's high affinity toward β1-integrin.
Sci Rep ;2017
PMID

Vuorinen EM, Rajala NK, Rauhala HE, Nurminen AT, Hytönen VP, Kallioniemi A
Search for KPNA7 cargo proteins in human cells reveals MVP and ZNF414 as novel regulators of cancer cell growth.
Biochim Biophys Acta ;1863(1)211-219, 2017
PMID

Cancer Groups
Jorma Isola - Cancer Biology
Anne Kallioniemi - Cancer Genomics
Daniela Ungureanu - Cancer Signaling

Ampuja M, Kallioniemi A
Transcription factors-Intricate players of the bone morphogenetic protein signaling pathway.
Genes Chromosomes Cancer ;2017
PMID

Määttä KM, Nurminen R, Kankuri-Tammilehto M, Kallioniemi A, Laasanen SL, Schleutker J
Germline EMSY sequence alterations in hereditary breast cancer and ovarian cancer families.
BMC Cancer ;17(1)496, 2017
PMID

Kiiski JI, Tervasmäki A, Pelttari LM, Khan S, Mantere T, Pylkäs K, Mannermaa A, Tengström M, Kvist A, Borg Å, Kosma VM, Kallioniemi A, Schleutker J, Bützow R, Blomqvist C, Aittomäki K, Winqvist R, Nevanlinna H
FANCM mutation c.5791C>T is a risk factor for triple-negative breast cancer in the Finnish population.
Breast Cancer Res Treat ;2017
PMID

Mantere T, Tervasmäki A, Nurmi A, Rapakko K, Kauppila S, Tang J, Schleutker J, Kallioniemi A, Hartikainen JM, Mannermaa A, Nieminen P, Hanhisalo R, Lehto S, Suvanto M, Grip M, Jukkola-Vuorinen A, Tengström M, Auvinen P, Kvist A, Borg Å, Blomqvist C, Aittomäki K, Greenberg RA, Winqvist R, Nevanlinna H, Pylkäs K
Case-control analysis of truncating mutations in DNA damage response genes connects TEX15 and FANCD2 with hereditary breast cancer susceptibility.
Sci Rep ;7(1)681, 2017
PMID

Lehtinen L, Vainio P, Wikman H, Huhtala H, Mueller V, Kallioniemi A, Pantel K, Kronqvist P, Kallioniemi O, Carpèn O, Iljin K
PLA2G7 associates with hormone receptor negativity in clinical breast cancer samples and regulates epithelial-mesenchymal transition in cultured breast cancer cells.
J Pathol Clin Res ;3(2)123-138, 2017
PMID

Vuorinen EM, Rajala NK, Rauhala HE, Nurminen AT, Hytönen VP, Kallioniemi A
Search for KPNA7 cargo proteins in human cells reveals MVP and ZNF414 as novel regulators of cancer cell growth.
Biochim Biophys Acta ;1863(1)211-219, 2017
PMID

Puleo DE, Kucera K, Hammarén HM, Ungureanu D, Newton AS, Silvennoinen O, Jorgensen WL, Schlessinger J
Identification and Characterization of JAK2 Pseudokinase Domain Small Molecule Binders.
ACS Med Chem Lett ;8(6)618-621, 2017
PMID

Karvonen H, Niininen W, Murumägi A, Ungureanu D
Targeting ROR1 identifies new treatment strategies in hematological cancers.
Biochem Soc Trans ;45(2)457-464, 2017
PMID

Prostate Cancer Research Center (PCRC)

Högnäs G, Kivinummi K, Kallio HML, Hieta R, Ruusuvuori P, Koskenalho A, Kesseli J, Tammela TLJ, Riikonen J, Ilvesaro J, Kares S, Hirvikoski PP, Laurila M, Mirtti T, Nykter M, Kujala PM, Visakorpi T, Tolonen T, Bova GS
Feasibility of Prostate PAXgene Fixation for Molecular Research and Diagnostic Surgical Pathology: Comparison of Matched Fresh Frozen, FFPE, and PFPE Tissues.
Am J Surg Pathol ;2017
PMID

Granberg KJ, Annala M, Lehtinen B, Kesseli J, Haapasalo J, Ruusuvuori P, Yli-Harja O, Visakorpi T, Haapasalo H, Nykter M, Zhang W
Strong FGFR3 staining is a marker for FGFR3 fusions in diffuse gliomas.
Neuro Oncol ;19(9)1206-1216, 2017
PMID

Latonen L, Scaravilli M, Gillen A, Hartikainen S, Zhang FP, Ruusuvuori P, Kujala P, Poutanen M, Visakorpi T
In Vivo Expression of miR-32 Induces Proliferation in Prostate Epithelium.
Am J Pathol ;2017
PMID

Urbanucci A, Barfeld SJ, Kytölä V, Itkonen HM, Coleman IM, Vodák D, Sjöblom L, Sheng X, Tolonen T, Minner S, Burdelski C, Kivinummi KK, Kohvakka A, Kregel S, Takhar M, Alshalalfa M, Davicioni E, Erho N, Lloyd P, Karnes RJ, Ross AE, Schaeffer EM, Vander Griend DJ, Knapp S, Corey E, Feng FY, Nelson PS, Saatcioglu F, Knudsen KE, Tammela TLJ, Sauter G, Schlomm T, Nykter M, Visakorpi T, Mills IG
Androgen Receptor Deregulation Drives Bromodomain-Mediated Chromatin Alterations in Prostate Cancer.
Cell Rep ;19(10)2045-2059, 2017
PMID

Lehtinen B, Raita A, Kesseli J, Annala M, Nordfors K, Yli-Harja O, Zhang W, Visakorpi T, Nykter M, Haapasalo H, Granberg KJ
Clinical association analysis of ependymomas and pilocytic astrocytomas reveals elevated FGFR3 and FGFR1 expression in aggressive ependymomas.
BMC Cancer ;17(1)310, 2017
PMID

Valkonen M, Ruusuvuori P, Kartasalo K, Nykter M, Visakorpi T, Latonen L
Analysis of spatial heterogeneity in normal epithelium and preneoplastic alterations in mouse prostate tumor models.
Sci Rep ;2017
PMID

Carlsson S, Assel M, Ulmert D, Gerdtsson A, Hugosson J, Vickers A, Lilja H
Screening for Prostate Cancer Starting at Age 50-54 Years. A Population-based Cohort Study.
Eur Urol ;71(1)46-52, 2017
PMID

Bova GS
Cancer genomics: Human metastases under scrutiny.
Nature ;548(7667)287-288, 2017
PMID

Högnäs G, Kivinummi K, Kallio HML, Hieta R, Ruusuvuori P, Koskenalho A, Kesseli J, Tammela TLJ, Riikonen J, Ilvesaro J, Kares S, Hirvikoski PP, Laurila M, Mirtti T, Nykter M, Kujala PM, Visakorpi T, Tolonen T, Bova GS
Feasibility of Prostate PAXgene Fixation for Molecular Research and Diagnostic Surgical Pathology: Comparison of Matched Fresh Frozen, FFPE, and PFPE Tissues.
Am J Surg Pathol ;2017
PMID

Computational Biology
Matti Nykter - Computational Biology
Högnäs G, Kivinummi K, Kallio HML, Hieta R, Ruusuvuori P, Koskenalho A, Kesseli J, Tammela TLJ, Riikonen J, Ilvesaro J, Kares S, Hirvikoski PP, Laurila M, Mirtti T, Nykter M, Kujala PM, Visakorpi T, Tolonen T, Bova GS
Feasibility of Prostate PAXgene Fixation for Molecular Research and Diagnostic Surgical Pathology: Comparison of Matched Fresh Frozen, FFPE, and PFPE Tissues.
Am J Surg Pathol ;2017
PMID

Nättinen J, Jylhä A, Aapola U, Enríquez-de-Salamanca A, Pinto-Fraga J, López-Miguel A, González-García MJ, Stern ME, Calonge M, Zhou L, Nykter M, Uusitalo H, Beuerman R
Topical fluorometholone treatment and desiccating stress change inflammatory protein expression in tears.
Ocul Surf ;2017
PMID

Hyysalo A, Ristola M, Mäkinen ME, Häyrynen S, Nykter M, Narkilahti S
Laminin α5 substrates promote survival, network formation and functional development of human pluripotent stem cell-derived neurons in vitro.
Stem Cell Res ;2017
PMID

Granberg KJ, Annala M, Lehtinen B, Kesseli J, Haapasalo J, Ruusuvuori P, Yli-Harja O, Visakorpi T, Haapasalo H, Nykter M, Zhang W
Strong FGFR3 staining is a marker for FGFR3 fusions in diffuse gliomas.
Neuro Oncol ;19(9)1206-1216, 2017
PMID

Kytola V, Topaloglu U, Miller LD, Bitting RL, Goodman MM, D Agostino RB, Desnoyers RJ, Albright C, Yacoub G, Qasem SA, DeYoung B, Thorsson V, Shmulevich I, Yang M, Shcherban A, Pagni M, Liu L, Nykter M, Chen K, Hawkins GA, Grant SC, Petty WJ, Alistar AT, Levine EA, Staren ED, Langefeld CD, Miller V, Singal G, Petro RM, Robinson M, Blackstock W, Powell BL, Wagner LI, Foley KL, Abraham E, Pasche B, Zhang W
Mutational Landscapes of Smoking-Related Cancers in Caucasians and African Americans: Precision Oncology Perspectives at Wake Forest Baptist Comprehensive Cancer Center.
Theranostics ;7(11)2914-2923, 2017
PMID

Vandekerkhove GR, Todenhöfer T, Annala M, Struss WJ, Wong A, Beja K, Ritch E, Brahmbhatt S, Volik S, Hennenlotter J, Nykter M, Chi KN, North S, Stenzl A, Collins CC, Eigl BJ, Black PC, Wyatt AW
Circulating tumor DNA reveals clinically-actionable somatic genome of metastatic bladder cancer.
Clin Cancer Res ;2017
PMID

Annala M, Struss WJ, Warner EW, Beja K, Vandekerkhove G, Wong A, Khalaf D, Seppälä IL, So A, Lo G, Aggarwal R, Small EJ, Nykter M, Gleave ME, Chi KN, Wyatt AW
Treatment Outcomes and Tumor Loss of Heterozygosity in Germline DNA Repair-deficient Prostate Cancer.
Eur Urol ;72(1)34-42, 2017
PMID

Tarkkonen K, Hieta R, Kytölä V, Nykter M, Kiviranta R
Comparative analysis of osteoblast gene expression profiles and Runx2 genomic occupancy of mouse and human osteoblasts in vitro.
Gene ;2017
PMID

Valkonen M, Kartasalo K, Liimatainen K, Nykter M, Latonen L, Ruusuvuori P
Metastasis detection from whole slide images using local features and random forests.
Cytometry A ;91(6)555-565, 2017
PMID

Lund RJ, Rahkonen N, Malonzo M, Kauko L, Emani MR, Kivinen V, Närvä E, Kemppainen E, Laiho A, Skottman H, Hovatta O, Rasool O, Nykter M, Lähdesmäki H, Lahesmaa R
RNA Polymerase III Subunit POLR3G Regulates Specific Subsets of PolyA(+) and SmallRNA Transcriptomes and Splicing in Human Pluripotent Stem Cells.
Stem Cell Reports ;8(5)1442-1454, 2017
PMID

Lehtinen B, Raita A, Kesseli J, Annala M, Nordfors K, Yli-Harja O, Zhang W, Visakorpi T, Nykter M, Haapasalo H, Granberg KJ
Clinical association analysis of ependymomas and pilocytic astrocytomas reveals elevated FGFR3 and FGFR1 expression in aggressive ependymomas.
BMC Cancer ;17(1)310, 2017
PMID

Urbanucci A, Barfeld SJ, Kytölä V, Itkonen HM, Coleman IM, Vodák D, Sjöblom L, Sheng X, Tolonen T, Minner S, Burdelski C, Kivinummi KK, Kohvakka A, Kregel S, Takhar M, Alshalalfa M, Davicioni E, Erho N, Lloyd P, Karnes RJ, Ross AE, Schaeffer EM, Vander Griend DJ, Knapp S, Corey E, Feng FY, Nelson PS, Saatcioglu F, Knudsen KE, Tammela TLJ, Sauter G, Schlomm T, Nykter M, Visakorpi T, Mills IG
Androgen Receptor Deregulation Drives Bromodomain-Mediated Chromatin Alterations in Prostate Cancer.
Cell Rep ;19(10)2045-2059, 2017
PMID

Lin J, Kramna L, Autio R, Hyöty H, Nykter M, Cinek O
Vipie: web pipeline for parallel characterization of viral populations from multiple NGS samples.
BMC Genomics ;18(1)378, 2017
PMID

Yang M, Topaloglu U, Petty WJ, Pagni M, Foley KL, Grant SC, Robinson M, Bitting RL, Thomas A, Alistar AT, Desnoyers RJ, Goodman M, Albright C, Porosnicu M, Vatca M, Qasem SA, DeYoung B, Kytola V, Nykter M, Chen K, Levine EA, Staren ED, D'Agostino RB, Petro RM, Blackstock W, Powell BL, Abraham E, Pasche B, Zhang W
Circulating mutational portrait of cancer: manifestation of aggressive clonal events in both early and late stages.
J Hematol Oncol ;10(1)100, 2017
PMID

Valkonen M, Ruusuvuori P, Kartasalo K, Nykter M, Visakorpi T, Latonen L
Analysis of spatial heterogeneity in normal epithelium and preneoplastic alterations in mouse prostate tumor models.
Sci Rep ;2017
PMID

Grönroos T, Teppo S, Mehtonen J, Laukkanen S, Liuksiala T, Nykter M, Heinäniemi M, Lohi O
Overexpression of PTP4A3 in ETV6-RUNX1 acute lymphoblastic leukemia.
Leuk Res ;2017
PMID

Afyounian E, Annala M, Nykter M
Segmentum: a tool for copy number analysis of cancer genomes.
BMC Bioinformatics ;18(1)215, 2017
PMID

Mitochondrial Genetics
Howy Jacobs - Mitochondrial Gene Expression and Disease Group
Saari S, Andjelković A, Garcia GS, Jacobs HT, Oliveira MT
Expression of Ciona intestinalis AOX causes male reproductive defects in Drosophila melanogaster.
BMC Dev Biol ;17(1)9, 2017
PMID

Salminen TS, Oliveira MT, Cannino G, Lillsunde P, Jacobs HT, Kaguni LS
Mitochondrial genotype modulates mtDNA copy number and organismal phenotype in Drosophila.
Mitochondrion ;2017
PMID

Molecular Immunology
Marko Pesu - Immunoregulation
Mika Rämet - Experimental Immunology
Vähätupa M, Cordova ZM, Aittomäki S, Uusitalo H, Järvinen TAH, Pesu M, Uusitalo-Järvinen H
Furin deficiency in myeloid cellsleads to attenuated revascularization in a mouse-model of oxygen-induced retinopathy.
Exp Eye Res ;2017
PMID

Aittomäki S, Valanne S, Lehtinen T, Matikainen S, Nyman TA, Rämet M, Pesu M
Proprotein convertase Furin1 expression in the Drosophila fat body is essential for a normal antimicrobial peptide response and bacterial host defense.
FASEB J ;2017
PMID

Kummola L, Ortutay Z, Chen X, Caucheteux S, Hämäläinen S, Aittomäki S, Yagi R, Zhu J, Pesu M, Paul WE, Junttila IS
IL-7Rα Expression Regulates Murine Dendritic Cell Sensitivity to Thymic Stromal Lymphopoietin.
J Immunol ;198(10)3909-3918, 2017
PMID

Myllymäki H, Niskanen M, Oksanen KE, Sherwood E, Ahava M, Parikka M, Rämet M
Identification of novel antigen candidates for a tuberculosis vaccine in the adult zebrafish (Danio rerio).
PLoS One ;12(7)e0181942, 2017
PMID

Aittomäki S, Valanne S, Lehtinen T, Matikainen S, Nyman TA, Rämet M, Pesu M
Proprotein convertase Furin1 expression in the Drosophila fat body is essential for a normal antimicrobial peptide response and bacterial host defense.
FASEB J ;2017
PMID

Khashana A, Ahmed H, Ahmed A, Abdelwahab A, Saarela T, Rämet M, Hallman M
Cortisol precursors in neonates with vasopressor-resistant hypotension in relationship to demographic characteristics.
J Matern Fetal Neonatal Med ;2017
PMID

Khashana A, Saarela T, Ramet M, Hallman M
Cortisol intermediates and hydrocortisone responsiveness in critical neonatal disease.
J Matern Fetal Neonatal Med ;30(14)1721-1725, 2017
PMID

Zhang G, Feenstra B, Bacelis J, Liu X, Muglia LM, Juodakis J, Miller DE, Litterman N, Jiang PP, Russell L, Hinds DA, Hu Y, Weirauch MT, Chen X, Chavan AR, Wagner GP, Pavličev M, Nnamani MC, Maziarz J, Karjalainen MK, Rämet M, Sengpiel V, Geller F, Boyd HA, Palotie A, Momany A, Bedell B, Ryckman KK, Huusko JM, Forney CR, Kottyan LC, Hallman M, Teramo K, Nohr EA, Davey Smith G, Melbye M, Jacobsson B, Muglia LJ
Genetic Associations with Gestational Duration and Spontaneous Preterm Birth.
N Engl J Med ;377(12)1156-1167, 2017
PMID

Mahlman M, Karjalainen MK, Huusko JM, Andersson S, Kari MA, Tammela OKT, Sankilampi U, Lehtonen L, Marttila RH, Bassler D, Poets CF, Lacaze-Masmonteil T, Danan C, Delacourt C, Palotie A, Muglia LJ, Lavoie PM, Hadchouel A, Rämet M, Hallman M
Genome-wide association study of bronchopulmonary dysplasia: a potential role for variants near the CRP gene.
Sci Rep ;7(1)9271, 2017
PMID

Pasanen A, Karjalainen MK, Bont L, Piippo-Savolainen E, Ruotsalainen M, Goksör E, Kumawat K, Hodemaekers H, Nuolivirta K, Jartti T, Wennergren G, Hallman M, Rämet M, Korppi M
Genome-Wide Association Study of Polymorphisms Predisposing to Bronchiolitis.
Sci Rep ;2017
PMID

Regenerative Medicine
Katriina Aalto-Setälä - Cardiology Group
Susanna Miettinen - Adult Stem Cell Group
Susanna Narkilahti - Neuro Group
Heli Skottman - Eye Group
Ahola A, Pölönen RP, Aalto-Setälä K, Hyttinen J
Simultaneous Measurement of Contraction and Calcium Transients in Stem Cell Derived Cardiomyocytes.
Ann Biomed Eng ;2017
PMID

Kiamehr M, Viiri LE, Vihervaara T, Koistinen KM, Hilvo M, Ekroos K, Käkelä R, Aalto-Setälä K
Lipidomic profiling of patient-specific iPSC-derived hepatocyte-like cells.
Dis Model Mech ;10(9)1141-1153, 2017
PMID

Vanninen SUM, Nikus K, Aalto-Setälä K
Electrocardiogram changes and atrial arrhythmias in individuals carrying sodium channel SCN5A D1275N mutation.
Ann Med ;49(6)496-503, 2017
PMID

Kuusela J, Larsson K, Shah D, Prajapati C, Aalto-Setälä K
Low extracellular potassium prolongs repolarization and evokes early afterdepolarization in human induced pluripotent stem cell-derived cardiomyocytes.
Biol Open ;6(6)777-784, 2017
PMID

Vuorenpää H, Penttinen K, Heinonen T, Pekkanen-Mattila M, Sarkanen JR, Ylikomi T, Aalto-Setälä K
Maturation of human pluripotent stem cell derived cardiomyocytes is improved in cardiovascular construct.
Cytotechnology ;2017
PMID

Virjula S, Zhao F, Leivo J, Vanhatupa S, Kreutzer J, Vaughan TJ, Honkala AM, Viehrig M, Mullen CA, Kallio P, McNamara LM, Miettinen S
The effect of equiaxial stretching on the osteogenic differentiation and mechanical properties of human adipose stem cells.
J Mech Behav Biomed Mater ;2017
PMID

Thesleff T, Lehtimäki K, Niskakangas T, Huovinen S, Mannerström B, Miettinen S, Seppänen-Kaijansinkko R, Öhman J
Cranioplasty with Adipose-Derived Stem Cells, Beta-Tricalcium Phosphate Granules and Supporting Mesh: Six-Year Clinical Follow-Up Results.
Stem Cells Transl Med ;6(7)1576-1582, 2017
PMID

Leivo J, Virjula S, Vanhatupa S, Kartasalo K, Kreutzer J, Miettinen S, Kallio P
A durable and biocompatible ascorbic acid-based covalent coating method of polydimethylsiloxane for dynamic cell culture.
J R Soc Interface ;2017
PMID

Sartoneva R, Nordback PH, Haimi S, Grijpma DW, Lehto K, Rooney N, Seppänen-Kaijansinkko R, Miettinen S, Lahdes-Vasama T
Comparison of Poly(l-lactide-co-ɛ-caprolactone) and Poly(trimethylene carbonate) Membranes for Urethral Regeneration: An In vitro and In vivo Study.
Tissue Eng Part A ;2017
PMID

Björninen M, Gilmore K, Pelto J, Seppänen-Kaijansinkko R, Kellomäki M, Miettinen S, Wallace G, Grijpma D, Haimi S
Electrically Stimulated Adipose Stem Cells on Polypyrrole-Coated Scaffolds for Smooth Muscle Tissue Engineering.
Ann Biomed Eng ;45(4)1015-1026, 2017
PMID

Patrikoski M, Lee MHC, Mäkinen L, Ang XM, Mannerström B, Raghunath M, Miettinen S
Effects of Macromolecular Crowding on Human Adipose Stem Cell Culture in Fetal Bovine Serum, Human Serum, and Defined Xeno-Free/Serum-Free Conditions.
Stem Cells Int ;2017
PMID

Hyysalo A, Ristola M, Mäkinen ME, Häyrynen S, Nykter M, Narkilahti S
Laminin α5 substrates promote survival, network formation and functional development of human pluripotent stem cell-derived neurons in vitro.
Stem Cell Res ;2017
PMID

Turunen S, Joki T, Hiltunen ML, Ihalainen TO, Narkilahti S, Kellomäki M
Direct Laser Writing of Tubular Microtowers for 3D Culture of Human Pluripotent Stem Cell-Derived Neuronal Cells.
ACS Appl Mater Interfaces ;9(31)25717-25730, 2017
PMID

Hyysalo A, Ristola M, Joki T, Honkanen M, Vippola M, Narkilahti S
Aligned Poly(ε-caprolactone) Nanofibers Guide the Orientation and Migration of Human Pluripotent Stem Cell-Derived Neurons, Astrocytes, and Oligodendrocyte Precursor Cells In Vitro.
Macromol Biosci ;2017
PMID

Koivisto JT, Joki T, Parraga JE, Pääkkönen R, Ylä-Outinen L, Salonen L, Jönkkäri I, Peltola M, Ihalainen TO, Narkilahti S, Kellomäki M
Bioamine-crosslinked gellan gum hydrogel for neural tissue engineering.
Biomed Mater ;12(2)025014, 2017
PMID

Kreutzer J, Ylä-Outinen L, Mäki AJ, Ristola M, Narkilahti S, Kallio P
Cell culture chamber with gas supply for prolonged recording of human neuronal cells on microelectrode array.
J Neurosci Methods ;2017
PMID

Hongisto H, Jylhä A, Nättinen J, Rieck J, Ilmarinen T, Veréb Z, Aapola U, Beuerman R, Petrovski G, Uusitalo H, Skottman H
Comparative proteomic analysis of human embryonic stem cell-derived and primary human retinal pigment epithelium.
Sci Rep ;7(1)6016, 2017
PMID

Lund RJ, Rahkonen N, Malonzo M, Kauko L, Emani MR, Kivinen V, Närvä E, Kemppainen E, Laiho A, Skottman H, Hovatta O, Rasool O, Nykter M, Lähdesmäki H, Lahesmaa R
RNA Polymerase III Subunit POLR3G Regulates Specific Subsets of PolyA(+) and SmallRNA Transcriptomes and Splicing in Human Pluripotent Stem Cells.
Stem Cell Reports ;8(5)1442-1454, 2017
PMID

Juuti-Uusitalo K, Koskela A, Kivinen N, Viiri J, Hyttinen JMT, Reinisalo M, Koistinen A, Uusitalo H, Sinha D, Skottman H, Kaarniranta K
Autophagy Regulates Proteasome Inhibitor-Induced Pigmentation in Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells.
Int J Mol Sci ;2017
PMID

Calejo MT, Ilmarinen T, Vuorimaa-Laukkanen E, Talvitie E, Hakola HM, Skottman H, Kellomäki M
Langmuir-Schaefer film deposition onto honeycomb porous films for retinal tissue engineering.
Acta Biomater ;2017
PMID

Sorkio A, Haimi S, Verdoold V, Juuti-Uusitalo K, Grijpma D, Skottman H
Poly(trimethylene carbonate) as an elastic biodegradable film for human embryonic stem cell-derived retinal pigment epithelial cells.
J Tissue Eng Regen Med ;2017
PMID

 
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Last update: 20.9.2017 9.16 Muokkaa

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