IBT julkaisut 2009
NOTE: This list is not exhaustive because it has been collected by an automatic procedure from PubMed. It may also contain publications not related to IMT or Regea authors (authors having the same name). The same publication may also appear more than once in case several research groups have participated in the writing. |
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Bioinformatics Mauno Vihinen - Bioinformatics Group |
| Cotton RG, Al Aqeel AI, Al-Mulla F, Carrera P, Claustres M, Ekong R, Hyland VJ, Macrae FA, Marafie MJ, Paalman MH, Patrinos GP, Qi M, Ramesar RS, Scott RJ, Sijmons RH, Sobrido MJ, Vihinen M, Capturing all disease-causing mutations for clinical and research use: toward an effortless system for the Human Variome Project. Genet Med 2009 ;11(12)843-9 PMID |
| Samarghitean C, Ortutay C, Vihinen M Systematic classification of primary immunodeficiencies based on clinical, pathological, and laboratory parameters. J Immunol 2009 ;183(11)7569-75 PMID |
| Samarghitean C, Vihinen M Bioinformatics services related to diagnosis of primary immunodeficiencies. Curr Opin Allergy Clin Immunol 2009 ;9(6)531-6 PMID |
| Qi CJ, Zheng L, Ma HB, Fei M, Qian KQ, Shen BR, Wu CP, Vihinen M, Zhang XG A novel mutation in CD40 and its functional characterization. Hum Mutat 2009 ;30(6)985-94 PMID |
| Liu W, Laitinen S, Khan S, Vihinen M, Kowalski J, Yu G, Chen L, Ewing CM, Eisenberger MA, Carducci MA, Nelson WG, Yegnasubramanian S, Luo J, Wang Y, Xu J, Isaacs WB, Visakorpi T, Bova GS Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer. Nat Med 2009 ;15(5)559-65 PMID |
| Laurila K, Vihinen M Prediction of disease-related mutations affecting protein localization. BMC Genomics 2009 ;10122 PMID |
| Kaput J, Cotton RG, Hardman L, Watson M, Al Aqeel AI, Al-Aama JY, Al-Mulla F, Alonso S, Aretz S, Auerbach AD, Bapat B, Bernstein IT, Bhak J, Bleoo SL, Blöcker H, Brenner SE, Burn J, Bustamante M, Calzone R, Cambon-Thomsen A, Cargill M, Carrera P, Cavedon L, Cho YS, Chung YJ, Claustres M, Cutting G, Dalgleish R, den Dunnen JT, Díaz C, Dobrowolski S, dos Santos MR, Ekong R, Flanagan SB, Flicek P, Furukawa Y, Genuardi M, Ghang H, Golubenko MV, Greenblatt MS, Hamosh A, Hancock JM, Hardison R, Harrison TM, Hoffmann R, Horaitis R, Howard HJ, Barash CI, Izagirre N, Jung J, Kojima T, Laradi S, Lee YS, Lee JY, Gil-da-Silva-Lopes VL, Macrae FA, Maglott D, Marafie MJ, Marsh SG, Matsubara Y, Messiaen LM, Möslein G, Netea MG, Norton ML, Oefner PJ, Oetting WS, O'Leary JC, de Ramirez AM, Paalman MH, Parboosingh J, Patrinos GP, Perozzi G, Phillips IR, Povey S, Prasad S, Qi M, Quin DJ, Ramesar RS, Richards CS, Savige J, Scheible DG, Scott RJ, Seminara D, Shephard EA, Sijmons RH, Smith TD, Sobrido MJ, Tanaka T, Tavtigian SV, Taylor GR, Teague J, Töpel T, Ullman-Cullere M, Utsunomiya J, van Kranen HJ, Vihinen M, Webb E, Weber TK, Yeager M, Yeom YI, Yim SH, Yoo HS, Planning the human variome project: the Spain report. Hum Mutat 2009 ;30(4)496-510 PMID |
| den Dunnen JT, Sijmons RH, Andersen PS, Vihinen M, Beckmann JS, Rossetti S, Talbot CC, Hardison RC, Povey S, Cotton RG Sharing data between LSDBs and central repositories. Hum Mutat 2009 ;30(4)493-5 PMID |
| Mohamed AJ, Yu L, Bäckesjö CM, Vargas L, Faryal R, Aints A, Christensson B, Berglöf A, Vihinen M, Nore BF, Smith CI Bruton's tyrosine kinase (Btk): function, regulation, and transformation with special emphasis on the PH domain. Immunol Rev 2009 ;228(1)58-73 PMID |
| Thusberg J, Vihinen M Pathogenic or not? And if so, then how? Studying the effects of missense mutations using bioinformatics methods. Hum Mutat 2009 ;30(5)703-14 PMID |
| Ortutay C, Vihinen M Immunome knowledge base (IKB): an integrated service for immunome research. BMC Immunol 2009 ;103 PMID |
| Vihinen M Problems with anti-plagiarism database. Nature 2009 ;457(7225)26 PMID |
| Ortutay C, Vihinen M Identification of candidate disease genes by integrating Gene Ontologies and protein-interaction networks: case study of primary immunodeficiencies. Nucleic Acids Res 2009 ;37(2)622-8 PMID |
| Stenberg KA, Vihinen M Crystal structure of a 1.6-hexanediol bound tetrameric form of Escherichia coli lac-repressor refined to 2.1 A resolution. Proteins 2009 ;75(3)748-59 PMID |
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Biotechnology Vesa Hytönen - Protein Dynamics Markku Kulomaa - Molecular Biotechnology |
| Saltel F, Mortier E, Hytönen VP, Jacquier MC, Zimmermann P, Vogel V, Liu W, Wehrle-Haller B New PI(4,5)P2- and membrane proximal integrin-binding motifs in the talin head control beta3-integrin clustering. J Cell Biol 2009 ;187(5)715-31 PMID |
| Määttä JA, Helppolainen SH, Hytönen VP, Johnson MS, Kulomaa MS, Airenne TT, Nordlund HR Structural and functional characteristics of xenavidin, the first frog avidin from Xenopus tropicalis. BMC Struct Biol 2009 ;963 PMID |
| Meir A, Helppolainen SH, Podoly E, Nordlund HR, Hytönen VP, Määttä JA, Wilchek M, Bayer EA, Kulomaa MS, Livnah O Crystal structure of rhizavidin: insights into the enigmatic high-affinity interaction of an innate biotin-binding protein dimer. J Mol Biol 2009 ;386(2)379-90 PMID |
| Määttä JA, Helppolainen SH, Hytönen VP, Johnson MS, Kulomaa MS, Airenne TT, Nordlund HR Structural and functional characteristics of xenavidin, the first frog avidin from Xenopus tropicalis. BMC Struct Biol 2009 ;963 PMID |
| Hilvo M, Salzano AM, Innocenti A, Kulomaa MS, Scozzafava A, Scaloni A, Parkkila S, Supuran CT Cloning, expression, post-translational modifications and inhibition studies on the latest mammalian carbonic anhydrase isoform, CA XV. J Med Chem 2009 ;52(3)646-54 PMID |
| Meir A, Helppolainen SH, Podoly E, Nordlund HR, Hytönen VP, Määttä JA, Wilchek M, Bayer EA, Kulomaa MS, Livnah O Crystal structure of rhizavidin: insights into the enigmatic high-affinity interaction of an innate biotin-binding protein dimer. J Mol Biol 2009 ;386(2)379-90 PMID |
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Cancer Groups Jorma Isola - Cancer Biology Anne Kallioniemi - Cancer Genomics Tapio Visakorpi - Molecular Biology of Prostate Cancer Johanna Schleutker - Genetic Predisposition to Cancer |
| Joensuu H, Bono P, Kataja V, Alanko T, Kokko R, Asola R, Utriainen T, Turpeenniemi-Hujanen T, Jyrkkiö S, Möykkynen K, Helle L, Ingalsuo S, Pajunen M, Huusko M, Salminen T, Auvinen P, Leinonen H, Leinonen M, Isola J, Kellokumpu-Lehtinen PL Fluorouracil, epirubicin, and cyclophosphamide with either docetaxel or vinorelbine, with or without trastuzumab, as adjuvant treatments of breast cancer: final results of the FinHer Trial. J Clin Oncol 2009 ;27(34)5685-92 PMID |
| Côme C, Laine A, Chanrion M, Edgren H, Mattila E, Liu X, Jonkers J, Ivaska J, Isola J, Darbon JM, Kallioniemi O, Thézenas S, Westermarck J CIP2A is associated with human breast cancer aggressivity. Clin Cancer Res 2009 ;15(16)5092-100 PMID |
| Gong Y, Sweet W, Duh YJ, Greenfield L, Tarco E, Trivedi S, Symmans WF, Isola J, Sneige N Performance of chromogenic in situ hybridization on testing HER2 Status in breast carcinomas with chromosome 17 polysomy and equivocal (2+) herceptest results: a study of two institutions using the conventional and new ASCO/CAP scoring criteria. Am J Clin Pathol 2009 ;132(2)228-36 PMID |
| Maurer M, Su T, Saal LH, Koujak S, Hopkins BD, Barkley CR, Wu J, Nandula S, Dutta B, Xie Y, Chin YR, Kim DI, Ferris JS, Gruvberger-Saal SK, Laakso M, Wang X, Memeo L, Rojtman A, Matos T, Yu JS, Cordon-Cardo C, Isola J, Terry MB, Toker A, Mills GB, Zhao JJ, Murty VV, Hibshoosh H, Parsons R 3-Phosphoinositide-dependent kinase 1 potentiates upstream lesions on the phosphatidylinositol 3-kinase pathway in breast carcinoma. Cancer Res 2009 ;69(15)6299-306 PMID |
| Köninki K, Tanner M, Auvinen A, Isola J HER-2 positive breast cancer: decreasing proportion but stable incidence in Finnish population from 1982 to 2005. Breast Cancer Res 2009 ;11(3)R37 PMID |
| Juuti-Uusitalo K, Lindfors K, Mäki M, Patrikainen M, Isola J, Kaukinen K Inhibition of epithelial growth factor receptor signalling does not preserve epithelial barrier function after in vitro gliadin insult. Scand J Gastroenterol 2009 ;44(7)820-5 PMID |
| Gong Y, Sweet W, Duh YJ, Greenfield L, Fang Y, Zhao J, Tarco E, Symmans WF, Isola J, Sneige N Chromogenic in situ hybridization is a reliable method for detecting HER2 gene status in breast cancer: a multicenter study using conventional scoring criteria and the new ASCO/CAP recommendations. Am J Clin Pathol 2009 ;131(4)490-7 PMID |
| Korja M, Jokilammi A, Salmi TT, Kalimo H, Pelliniemi TT, Isola J, Rantala I, Haapasalo H, Finne J Absence of polysialylated NCAM is an unfavorable prognostic phenotype for advanced stage neuroblastoma. BMC Cancer 2009 ;957 PMID |
| Laurila M, Tammela TL, Auvinen A, Isola J, Visakorpi T, Luukkaala T, Määttänen L, Ruutu M, Ala-Opas M, Mildh M, Martikainen P Biological aggressiveness of prostate cancer in the Finnish screening trial. Int J Cancer 2009 ;124(3)547-52 PMID |
| Mäenpää J, Tanner M, Isola J Analyzing toposimerase II-alpha and HER-2/neu co-amplification seems to be of limited value in epithelial ovarian cancer. Acta Oncol 2009 ;48(4)617-9 PMID |
| Tuominen VJ, Isola J The application of JPEG2000 in virtual microscopy. J Digit Imaging 2009 ;22(3)250-8 PMID |
| Laurila E, Savinainen K, Kuuselo R, Karhu R, Kallioniemi A Characterization of the 7q21-q22 amplicon identifies ARPC1A, a subunit of the Arp2/3 complex, as a regulator of cell migration and invasion in pancreatic cancer. Genes Chromosomes Cancer 2009 ;48(4)330-9 PMID |
| Alarmo EL, Pärssinen J, Ketolainen JM, Savinainen K, Karhu R, Kallioniemi A BMP7 influences proliferation, migration, and invasion of breast cancer cells. Cancer Lett 2009 ;275(1)35-43 PMID |
| Waltering KK, Helenius MA, Sahu B, Manni V, Linja MJ, Jänne OA, Visakorpi T Increased expression of androgen receptor sensitizes prostate cancer cells to low levels of androgens. Cancer Res 2009 ;69(20)8141-9 PMID |
| Chi KN, Bjartell A, Dearnaley D, Saad F, Schröder FH, Sternberg C, Tombal B, Visakorpi T Castration-resistant prostate cancer: from new pathophysiology to new treatment targets. Eur Urol 2009 ;56(4)594-605 PMID |
| Liu W, Laitinen S, Khan S, Vihinen M, Kowalski J, Yu G, Chen L, Ewing CM, Eisenberger MA, Carducci MA, Nelson WG, Yegnasubramanian S, Luo J, Wang Y, Xu J, Isaacs WB, Visakorpi T, Bova GS Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer. Nat Med 2009 ;15(5)559-65 PMID |
| Saramäki OR, Waltering KK, Visakorpi T Methods for identifying and studying genetic alterations in hormone-dependent cancers. Methods Mol Biol 2009 ;505263-77 PMID |
| Laurila M, Tammela TL, Auvinen A, Isola J, Visakorpi T, Luukkaala T, Määttänen L, Ruutu M, Ala-Opas M, Mildh M, Martikainen P Biological aggressiveness of prostate cancer in the Finnish screening trial. Int J Cancer 2009 ;124(3)547-52 PMID |
| Jalava SE, Porkka KP, Rauhala HE, Isotalo J, Tammela TL, Visakorpi T TCEB1 promotes invasion of prostate cancer cells. Int J Cancer 2009 ;124(1)95-102 PMID |
| Pakkanen S, Wahlfors T, Siltanen S, Patrikainen M, Matikainen MP, Tammela TL, Schleutker J PALB2 variants in hereditary and unselected Finnish prostate cancer cases. J Negat Results Biomed 2009 ;812 PMID |
| Pakkanen S, Pukkala E, Kainulainen H, Matikainen MP, Koivisto PA, Tammela TL, Schleutker J Incidence of cancer in finnish families with clinically aggressive and nonaggressive prostate cancer. Cancer Epidemiol Biomarkers Prev 2009 ;18(11)3049-56 PMID |
| Gudmundsson J, Sulem P, Gudbjartsson DF, Blondal T, Gylfason A, Agnarsson BA, Benediktsdottir KR, Magnusdottir DN, Orlygsdottir G, Jakobsdottir M, Stacey SN, Sigurdsson A, Wahlfors T, Tammela T, Breyer JP, McReynolds KM, Bradley KM, Saez B, Godino J, Navarrete S, Fuertes F, Murillo L, Polo E, Aben KK, van Oort IM, Suarez BK, Helfand BT, Kan D, Zanon C, Frigge ML, Kristjansson K, Gulcher JR, Einarsson GV, Jonsson E, Catalona WJ, Mayordomo JI, Kiemeney LA, Smith JR, Schleutker J, Barkardottir RB, Kong A, Thorsteinsdottir U, Rafnar T, Stefansson K Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility. Nat Genet 2009 ;41(10)1122-6 PMID |
| Eeles RA, Kote-Jarai Z, Al Olama AA, Giles GG, Guy M, Severi G, Muir K, Hopper JL, Henderson BE, Haiman CA, Schleutker J, Hamdy FC, Neal DE, Donovan JL, Stanford JL, Ostrander EA, Ingles SA, John EM, Thibodeau SN, Schaid D, Park JY, Spurdle A, Clements J, Dickinson JL, Maier C, Vogel W, Dörk T, Rebbeck TR, Cooney KA, Cannon-Albright L, Chappuis PO, Hutter P, Zeegers M, Kaneva R, Zhang HW, Lu YJ, Foulkes WD, English DR, Leongamornlert DA, Tymrakiewicz M, Morrison J, Ardern-Jones AT, Hall AL, O'Brien LT, Wilkinson RA, Saunders EJ, Page EC, Sawyer EJ, Edwards SM, Dearnaley DP, Horwich A, Huddart RA, Khoo VS, Parker CC, Van As N, Woodhouse CJ, Thompson A, Christmas T, Ogden C, Cooper CS, Southey MC, Lophatananon A, Liu JF, Kolonel LN, Le Marchand L, Wahlfors T, Tammela TL, Auvinen A, Lewis SJ, Cox A, FitzGerald LM, Koopmeiners JS, Karyadi DM, Kwon EM, Stern MC, Corral R, Joshi AD, Shahabi A, McDonnell SK, Sellers TA, Pow-Sang J, Chambers S, Aitken J, Gardiner RA, Batra J, Kedda MA, Lose F, Polanowski A, Patterson B, Serth J, Meyer A, Luedeke M, Stefflova K, Ray AM, Lange EM, Farnham J, Khan H, Slavov C, Mitkova A, Cao G, , , , Easton DF Identification of seven new prostate cancer susceptibility loci through a genome-wide association study. Nat Genet 2009 ;41(10)1116-21 PMID |
| Mononen N, Schleutker J Polymorphisms in genes involved in androgen pathways as risk factors for prostate cancer. J Urol 2009 ;181(4)1541-9 PMID |
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Cellular Biology Ari-Pekka Huovila - Cell Interactions Herma Renkema - Biochemistry of Cell Signaling |
| Kleino I, Ortiz RM, Yritys M, Huovila AP, Saksela K Alternative splicing of ADAM15 regulates its interactions with cellular SH3 proteins. J Cell Biochem 2009 ;108(4)877-85 PMID |
| Levula M, Airla N, Oksala N, Hernesniemi JA, Pelto-Huikko M, Salenius JP, Zeitlin R, Järvinen O, Huovila AP, Nikkari ST, Jaakkola O, Ilveskoski E, Mikkelsson J, Perola M, Laaksonen R, Kytömäki L, Soini JT, Kähönen M, Parkkinen J, Karhunen PJ, Lehtimäki T ADAM8 and its single nucleotide polymorphism 2662 T/G are associated with advanced atherosclerosis and fatal myocardial infarction: Tampere vascular study. Ann Med 2009 ;41(7)497-507 PMID |
| Oksala N, Levula M, Airla N, Pelto-Huikko M, Ortiz RM, Järvinen O, Salenius JP, Ozsait B, Komurcu-Bayrak E, Erginel-Unaltuna N, Huovila AP, Kytömäki L, Soini JT, Kähönen M, Karhunen PJ, Laaksonen R, Lehtimäki T ADAM-9, ADAM-15, and ADAM-17 are upregulated in macrophages in advanced human atherosclerotic plaques in aorta and carotid and femoral arteries--Tampere vascular study. Ann Med 2009 ;41(4)279-90 PMID |
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Mitochondrial Genetics Howy Jacobs - Mitochondrial Gene Expression and Disease Group Hans Spelbrink - Molecular Biology-Mitochondrial DNA maintenance |
| Dassa EP, Dufour E, Gonçalves S, Paupe V, Hakkaart GA, Jacobs HT, Rustin P Expression of the alternative oxidase complements cytochrome c oxidase deficiency in human cells. EMBO Mol Med 2009 ;1(1)30-6 PMID |
| Fukuoh A, Ohgaki K, Hatae H, Kuraoka I, Aoki Y, Uchiumi T, Jacobs HT, Kang D DNA conformation-dependent activities of human mitochondrial RNA polymerase. Genes Cells 2009 ;14(8)1029-42 PMID |
| Kemppainen E, Fernández-Ayala DJ, Galbraith LC, O'Dell KM, Jacobs HT Phenotypic suppression of the Drosophila mitochondrial disease-like mutant tko(25t) by duplication of the mutant gene in its natural chromosomal context. Mitochondrion 2009 ;9(5)353-63 PMID |
| Pohjoismäki JL, Goffart S, Tyynismaa H, Willcox S, Ide T, Kang D, Suomalainen A, Karhunen PJ, Griffith JD, Holt IJ, Jacobs HT Human heart mitochondrial DNA is organized in complex catenated networks containing abundant four-way junctions and replication forks. J Biol Chem 2009 ;284(32)21446-57 PMID |
| Rustin P, Jacobs HT Respiratory chain alternative enzymes as tools to better understand and counteract respiratory chain deficiencies in human cells and animals. Physiol Plant 2009 ;137(4)362-70 PMID |
| Dassa EP, Dufour E, Goncalves S, Jacobs HT, Rustin P The alternative oxidase, a tool for compensating cytochrome c oxidase deficiency in human cells. Physiol Plant 2009 ;137(4)427-34 PMID |
| Zanotto E, Häkkinen A, Teku G, Shen B, Ribeiro AS, Jacobs HT NF-Y influences directionality of transcription from the bidirectional Mrps12/Sarsm promoter in both mouse and human cells. Biochim Biophys Acta 2009 ;1789(5)432-42 PMID |
| Fernandez-Ayala DJ, Sanz A, Vartiainen S, Kemppainen KK, Babusiak M, Mustalahti E, Costa R, Tuomela T, Zeviani M, Chung J, O'Dell KM, Rustin P, Jacobs HT Expression of the Ciona intestinalis alternative oxidase (AOX) in Drosophila complements defects in mitochondrial oxidative phosphorylation. Cell Metab 2009 ;9(5)449-60 PMID |
| Di Re M, Sembongi H, He J, Reyes A, Yasukawa T, Martinsson P, Bailey LJ, Goffart S, Boyd-Kirkup JD, Wong TS, Fersht AR, Spelbrink JN, Holt IJ The accessory subunit of mitochondrial DNA polymerase gamma determines the DNA content of mitochondrial nucleoids in human cultured cells. Nucleic Acids Res 2009 ;37(17)5701-13 PMID |
| Duxin JP, Dao B, Martinsson P, Rajala N, Guittat L, Campbell JL, Spelbrink JN, Stewart SA Human Dna2 is a nuclear and mitochondrial DNA maintenance protein. Mol Cell Biol 2009 ;29(15)4274-82 PMID |
| Cooper HM, Huang JY, Verdin E, Spelbrink JN A new splice variant of the mouse SIRT3 gene encodes the mitochondrial precursor protein. PLoS One 2009 ;4(3)e4986 PMID |
| Goffart S, Cooper HM, Tyynismaa H, Wanrooij S, Suomalainen A, Spelbrink JN Twinkle mutations associated with autosomal dominant progressive external ophthalmoplegia lead to impaired helicase function and in vivo mtDNA replication stalling. Hum Mol Genet 2009 ;18(2)328-40 PMID |
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Molecular Immunology Dan Hultmark - Genetic Immunology Marko Pesu - Immunoregulation Mika Rämet - Experimental Immunology Olli Silvennoinen - Molecular Immunology |
| Habayeb MS, Ekström JO, Hultmark D Nora virus persistent infections are not affected by the RNAi machinery. PLoS One 2009 ;4(5)e5731 PMID |
| Steiner H, Hultmark D, Engström A, Bennich H, Boman HG Sequence and specificity of two antibacterial proteins involved in insect immunity. Nature 292: 246-248. 1981. J Immunol 2009 ;182(11)6635-7 PMID |
| Márkus R, Laurinyecz B, Kurucz E, Honti V, Bajusz I, Sipos B, Somogyi K, Kronhamn J, Hultmark D, Andó I Sessile hemocytes as a hematopoietic compartment in Drosophila melanogaster. Proc Natl Acad Sci U S A 2009 ;106(12)4805-9 PMID |
| Habayeb MS, Cantera R, Casanova G, Ekström JO, Albright S, Hultmark D The Drosophila Nora virus is an enteric virus, transmitted via feces. J Invertebr Pathol 2009 ;101(1)29-33 PMID |
| Wiklund ML, Steinert S, Junell A, Hultmark D, Stöven S The N-terminal half of the Drosophila Rel/NF-kappaB factor Relish, REL-68, constitutively activates transcription of specific Relish target genes. Dev Comp Immunol 2009 ;33(5)690-6 PMID |
| Sundström JF, Vaculova A, Smertenko AP, Savenkov EI, Golovko A, Minina E, Tiwari BS, Rodriguez-Nieto S, Zamyatnin AA, Välineva T, Saarikettu J, Frilander MJ, Suarez MF, Zavialov A, Ståhl U, Hussey PJ, Silvennoinen O, Sundberg E, Zhivotovsky B, Bozhkov PV Tudor staphylococcal nuclease is an evolutionarily conserved component of the programmed cell death degradome. Nat Cell Biol 2009 ;11(11)1347-54 PMID |
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Regenerative Medicine Katriina Aalto-Setälä - Cardiology Group Susanna Miettinen - Adult Stem Cell Group Susanna Narkilahti - Neuro Group Heli Skottman - Ophthalmology Group |
| Aalto-Setälä K, Conklin BR, Lo B Obtaining consent for future research with induced pluripotent cells: opportunities and challenges. PLoS Biol 2009 ;7(2)e42 PMID |
| Pekkanen-Mattila M, Kerkelä E, Tanskanen JM, Pietilä M, Pelto-Huikko M, Hyttinen J, Skottman H, Suuronen R, Aalto-Setälä K Substantial variation in the cardiac differentiation of human embryonic stem cell lines derived and propagated under the same conditions--a comparison of multiple cell lines. Ann Med 2009 ;41(5)360-70 PMID |
| Lindroos B, Boucher S, Chase L, Kuokkanen H, Huhtala H, Haataja R, Vemuri M, Suuronen R, Miettinen S Serum-free, xeno-free culture media maintain the proliferation rate and multipotentiality of adipose stem cells in vitro. Cytotherapy 2009 ;11(7)958-72 PMID |
| Miettinen S, Ylikomi T Concomitant exposure of ovarian cancer cells to docetaxel, CPT-11 or SN-38 and adenovirus-mediated p53 gene therapy. Anticancer Drugs 2009 ;20(7)589-600 PMID |
| Haimi S, Gorianc G, Moimas L, Lindroos B, Huhtala H, Räty S, Kuokkanen H, Sándor GK, Schmid C, Miettinen S, Suuronen R Characterization of zinc-releasing three-dimensional bioactive glass scaffolds and their effect on human adipose stem cell proliferation and osteogenic differentiation. Acta Biomater 2009 ;5(8)3122-31 PMID |
| Miettinen S, Grènman S, Ylikomi T Inhibition of P-glycoprotein-mediated docetaxel efflux sensitizes ovarian cancer cells to concomitant docetaxel and SN-38 exposure. Anticancer Drugs 2009 ;20(4)267-76 PMID |
| Haimi S, Suuriniemi N, Haaparanta AM, Ellä V, Lindroos B, Huhtala H, Räty S, Kuokkanen H, Sándor GK, Kellomäki M, Miettinen S, Suuronen R Growth and osteogenic differentiation of adipose stem cells on PLA/bioactive glass and PLA/beta-TCP scaffolds. Tissue Eng Part A 2009 ;15(7)1473-80 PMID |
| Haimi S, Moimas L, Pirhonen E, Lindroos B, Huhtala H, Räty S, Kuokkanen H, Sándor GK, Miettinen S, Suuronen R Calcium phosphate surface treatment of bioactive glass causes a delay in early osteogenic differentiation of adipose stem cells. J Biomed Mater Res A 2009 ;91(2)540-7 PMID |
| Narkilahti S, Hovatta O, Elovaara I [Stem cells in therapy of multiple sclerosis]. Duodecim 2009 ;125(9)965-73 PMID |
| Heikkilä TJ, Ylä-Outinen L, Tanskanen JM, Lappalainen RS, Skottman H, Suuronen R, Mikkonen JE, Hyttinen JA, Narkilahti S Human embryonic stem cell-derived neuronal cells form spontaneously active neuronal networks in vitro. Exp Neurol 2009 ;218(1)109-16 PMID |
| Sundberg M, Jansson L, Ketolainen J, Pihlajamäki H, Suuronen R, Skottman H, Inzunza J, Hovatta O, Narkilahti S CD marker expression profiles of human embryonic stem cells and their neural derivatives, determined using flow-cytometric analysis, reveal a novel CD marker for exclusion of pluripotent stem cells. Stem Cell Res 2009 ;2(2)113-24 PMID |
| Hicks AU, Lappalainen RS, Narkilahti S, Suuronen R, Corbett D, Sivenius J, Hovatta O, Jolkkonen J Transplantation of human embryonic stem cell-derived neural precursor cells and enriched environment after cortical stroke in rats: cell survival and functional recovery. Eur J Neurosci 2009 ;29(3)562-74 PMID |
| Zhang P, Zucchelli M, Bruce S, Hambiliki F, Stavreus-Evers A, Levkov L, Skottman H, Kerkelä E, Kere J, Hovatta O Transcriptome profiling of human pre-implantation development. PLoS One 2009 ;4(11)e7844 PMID |
| Heikkilä TJ, Ylä-Outinen L, Tanskanen JM, Lappalainen RS, Skottman H, Suuronen R, Mikkonen JE, Hyttinen JA, Narkilahti S Human embryonic stem cell-derived neuronal cells form spontaneously active neuronal networks in vitro. Exp Neurol 2009 ;218(1)109-16 PMID |
| Sundberg M, Jansson L, Ketolainen J, Pihlajamäki H, Suuronen R, Skottman H, Inzunza J, Hovatta O, Narkilahti S CD marker expression profiles of human embryonic stem cells and their neural derivatives, determined using flow-cytometric analysis, reveal a novel CD marker for exclusion of pluripotent stem cells. Stem Cell Res 2009 ;2(2)113-24 PMID |
| Pekkanen-Mattila M, Kerkelä E, Tanskanen JM, Pietilä M, Pelto-Huikko M, Hyttinen J, Skottman H, Suuronen R, Aalto-Setälä K Substantial variation in the cardiac differentiation of human embryonic stem cell lines derived and propagated under the same conditions--a comparison of multiple cell lines. Ann Med 2009 ;41(5)360-70 PMID |
| Hakala H, Rajala K, Ojala M, Panula S, Areva S, Kellomäki M, Suuronen R, Skottman H Comparison of biomaterials and extracellular matrices as a culture platform for multiple, independently derived human embryonic stem cell lines. Tissue Eng Part A 2009 ;15(7)1775-85 PMID |
Biolääketieteellisen teknologian yksikkö
Biokatu 8
33520 Tampere, Finland
Biokatu 8
33520 Tampere, Finland
