Uutiset

● NC3Rs e-newsletter - Issue 18

● TSAR : Tracking System for Alternative test methods Review, Validation and Approval in the Context of EU Regulations on Chemicals

● Eläinkokeiden vaihtoehtohakukone on käytettävissä:  www.go3r.org

● Ecopan uutislehti (ecopa messenger)

● ECVAMin tietokanta eläinkokeille vaihtoehtoisista menetelmistä  (DB-ALM):
http://ecvam-dbalm.jrc.ec.europa.eu/

● DB-ALM News 31108
DB-ALM publishes new information
It’s our pleasure to inform you that further information sheets have been finalised by the DB-ALM and its collaborators and are now available online for the topic area of: Hepatotoxicity/metabolism-mediated toxicity
The following descriptions of in-vitro techniques using the below listed experimental systems have been either updated or newly added to the DB-ALM info content. They include information on their objectives & applications, rationale, basic procedure and status of development and/or validation and all are based on extensive literature reviews. For each technique related information is also provided.
Complete list of new and/or updated information sheets available online:

• Co-culture of primary hepatocytes with another cell type – Summary
• Genomics technology to investigate hepatotoxicity in vitro – Summary
• Hepatocyte cultures on biosensor systems – Summary
• Monolayer culture of genetically engineered liver cell lines – Summary
• Monolayer culture of liver cell lines – Summary
• Perfused three-dimensional culture systems ( bioreactors) with liver cells – Summary
• Perfused two-dimensional culture systems ( bioreactors) with liver cells – Summary
• The technique of hepatocyte isolation and cryopreservation - Summary
• The use of avian embryonic tissue for studies on metabolism and metabolism-mediated toxicity of chemicals – Summary
• The use of stem or progenitor cell-derived hepatocyte-like cells – Summary
• The use of subcellular fractions of liver tissue and liver homogenate – Summary

Now, for the above topic area the DB-ALM provides 23 new and/or updated information sheeets on-line on in vitro techniques toghether with more than 4175 test results.
We invite you to consult the whole sector by choosing “Method-Summaries” from the “In Vitro Methods Search” option on the DB-ALM homepage.
For more information: dbalm-contact@jrc.it

● DB-ALM Newsletter 271108
Register on the "Who's who - data sector"

If you have not yet taken the opportunity to access the data sector of : “Persons & Institutions active in the Field of Alternative Methods." we wish to remind you that you can view the above information via the “In Vitro Methods" search option from the top menu bar.

The current data sector includes all persons which have recently confirmed/updated their data upon our request, in addition to the contact details available for the INVITTOX protocols.

We further wish to inform you that, in the future, we will contact all persons every 2 years in an automatic manner to verify and/or review their data. Those who don't reply after two reminders we will have to remove from the directory.

New registrations
To extend the availability of information on persons/institutions active in the animal alternatives field ("Who's who"), we invite you to send us a short alert to dbalm-contact@jrc.it stating your wish to become part of this service.
We will come soon back to you and submit you a predetermined form for completion.