To page body
university of tampere: faculty of medicine and life sciences: research:
Faculty of Medicine and Life SciencesUniversity of TampereFaculty of Medicine and Life Sciences

 

Heikki Hyöty valokuva.jpgVirology

 

 

Professor:

Heikki Hyöty, M.D., Ph.D.

puh. +385 (0)50 516 8480

Heikki.Hyoty@uta.fi

CV

Link to publications

Researchers:

Tel.

E-mail

Hanna Honkanen, M.Sc. +385 (0)50 318 6284 Hanna.Honkanen@uta.fi
Jutta Laiho, M.Sc. +385 (0)50 318 6338 Jutta.E.Laiho@uta.fi
Anita Kondrashova, M.D. +385 (0)50 318 6284 Anita.Kondrashova@uta.fi
Laura Korhonen, M.D. +385 (0)50 525 5889 Laura.M.Korhonen@uta.fi
Maria Lönnrot, M.D., Ph.D. +385 (0)50 466 2671 Maria.Lonnrot@uta.fi
Noora Nurminen, M.Sc. +385 (0)50 318 6284 Noora.Nurminen@uta.fi
Maarit Oikarinen, M.Sc. +385 (0)50 318 6338 Maarit.Oikarinen@uta.fi
Sami Oikarinen, M.Sc. +385 (0)50 318 6295 Sami.Oikarinen@uta.fi
Tapio Seiskari, M.D. +385 (0)50 375 5852 tapio.seiskari@pshp.fi
Amirbabak Sioofy-Khojine, D.V.M., Ph.D. +385 (0)50 318 6338 Amirbabak.Sioofy.Khojine@uta.fi
Hanna Viskari, M.D.  +385 (0)3 311 611 Hanna.Viskari@uta.fi

Project manager:

 
Leena Puustinen, M.Sc. +358 (0)50 318 6295 Leena.Puustinen@uta.fi

 Leikattu Mervi pipetoi.jpg

Laboratory:  

Tel. +358 (0)50 318 6262

Jalonen Eveliina  Eveliina.Jalonen@uta.fi
Karjalainen Anne   Anne.M.Karjalainen@uta.fi
Kekäläinen Mervi Mervi.Kekalainen@uta.fi
Keränen Pekka  Pekka.Keranen@uta.fi
Kuusela Tanja  Tanja.K.Kuusela@uta.fi
Lehtonen Jussi   Jussi.P.Lehtonen@uta.fi
Ovaskainen Maria  Maria.Ovaskainen@uta.fi
Tolvanen Eeva Eeva.Tolvanen@uta.fi


 

Research projects / Collaborators:

 

DIABIMMUNE TEDDY
DIPP TRIGR
nPOD VACTIA
PEVNET VIRDIAB

Uusimmat julkaisut:

Stewart CJ, Ajami NJ, O'Brien JL, Hutchinson DS, Smith DP, Wong MC, Ross MC, Lloyd RE, Doddapaneni H, Metcalf GA, Muzny D, Gibbs RA, Vatanen T, Huttenhower C, Xavier RJ, Rewers M, Hagopian W, Toppari J, Ziegler AG, She JX, Akolkar B, Lernmark A, Hyoty H, Vehik K, Krischer JP, Petrosino JF
Temporal development of the gut microbiome in early childhood from the TEDDY study.
Nature ;562(7728)583-588, 2018
PMID

Jääskeläinen AJ, Nurminen N, Kolehmainen P, Smura T, Tauriainen S, Toppari J, Ilonen J, Veijola R, Knip M, Hyöty H, Vapalahti O, Kallio-Kokko H
No Association Between Ljungan Virus Seropositivity and the Beta-Cell Damaging Process in the Finnish Type 1 Diabetes Prediction and Prevention Study Cohort.
Pediatr Infect Dis J ;2018
PMID

Ekman I, Vuorinen T, Knip M, Veijola R, Toppari J, Hyöty H, Kinnunen T, Ilonen J, Lempainen J
Early childhood CMV infection may decelerate the progression to clinical type 1 diabetes.
Pediatr Diabetes ;2018
PMID

Korhonen L, Seiskari T, Lehtonen J, Puustinen L, Surcel HM, Haapala AM, Niemelä O, Virtanen SM, Honkanen H, Karjalainen M, Ilonen J, Veijola R, Knip M, Lönnrot M, Hyöty H
Enterovirus infection during pregnancy is inversely associated with atopic disease in the offspring.
Clin Exp Allergy ;2018
PMID

Yassour M, Jason E, Hogstrom LJ, Arthur TD, Tripathi S, Siljander H, Selvenius J, Oikarinen S, Hyöty H, Virtanen SM, Ilonen J, Ferretti P, Pasolli E, Tett A, Asnicar F, Segata N, Vlamakis H, Lander ES, Huttenhower C, Knip M, Xavier RJ
Strain-Level Analysis of Mother-to-Child Bacterial Transmission during the First Few Months of Life.
Cell Host Microbe ;24(1)146-154.e4, 2018
PMID

Lamichhane S, Ahonen L, Dyrlund TS, Kemppainen E, Siljander H, Hyöty H, Ilonen J, Toppari J, Veijola R, Hyötyläinen T, Knip M, Oresic M
Dynamics of Plasma Lipidome in Progression to Islet Autoimmunity and Type 1 Diabetes - Type 1 Diabetes Prediction and Prevention Study (DIPP).
Sci Rep ;8(1)10635, 2018
PMID

Lind A, Lynch KF, Lundgren M, Lernmark Å, Almgren P, Ramelius A, Puustinen L, Hyöty H, Lundstig A
First trimester enterovirus IgM and beta cell autoantibodies in mothers to children affected by type 1 diabetes autoimmunity before 7 years of age.
J Reprod Immunol ;2018
PMID

Nurminen N, Lin J, Grönroos M, Puhakka R, Kramna L, Vari HK, Viskari H, Oikarinen S, Roslund M, Parajuli A, Tyni I, Cinek O, Laitinen O, Hyöty H, Sinkkonen A
Nature-derived microbiota exposure as a novel immunomodulatory approach.
Future Microbiol ;2018
PMID

Grönroos M, Parajuli A, Laitinen OH, Roslund MI, Vari HK, Hyöty H, Puhakka R, Sinkkonen A
Short-term direct contact with soil and plant materials leads to an immediate increase in diversity of skin microbiota.
Microbiologyopen ;2018
PMID

Sioofy-Khojine AB, Lehtonen J, Nurminen N, Laitinen OH, Oikarinen S, Huhtala H, Pakkanen O, Ruokoranta T, Hankaniemi MM, Toppari J, Vähä-Mäkilä M, Ilonen J, Veijola R, Knip M, Hyöty H
Coxsackievirus B1 infections are associated with the initiation of insulin-driven autoimmunity that progresses to type 1 diabetes.
Diabetologia ;61(5)1193-1202, 2018
PMID

Laitinen OH, Svedin E, Kapell S, Hankaniemi MM, Larsson PG, Domsgen E, Stone VM, Määttä JAE, Hyöty H, Hytönen VP, Flodström-Tullberg M
pro protease antibodies for virus detection and discovery of pathogenic mechanisms.
J Virol Methods ;2018
PMID

Kondrashova A, Nurminen N, Lehtonen J, Hyöty M, Toppari J, Ilonen J, Veijola R, Knip M, Hyöty H
Exocrine pancreas function decreases during the progression of the beta-cell damaging process in young prediabetic children.
Pediatr Diabetes ;19(3)398-402, 2018
PMID

Ponsonby AL, Pezic A, Cameron FJ, Rodda C, Kemp AS, Carlin JB, Hyoty H, Sioofy-Khojine A, Dwyer T, Ellis JA, Craig ME
Higher parental occupational social contact is associated with a reduced risk of incident pediatric type 1 diabetes: Mediation through molecular enteroviral indices.
PLoS One ;13(4)e0193992, 2018
PMID

Cinek O, Mazankova K, Kramna L, Odeh R, Alassaf A, Ibekwe MU, Ahmadov G, Mekki H, Abdullah MA, Elmahi BME, Hyöty H, Rainetova P
Quantitative CrAssphage real-time PCR assay derived from data of multiple geographically distant populations.
J Med Virol ;90(4)767-771, 2018
PMID

Roslund MI, Grönroos M, Rantalainen AL, Jumpponen A, Romantschuk M, Parajuli A, Hyöty H, Laitinen O, Sinkkonen A
Half-lives of PAHs and temporal microbiota changes in commonly used urban landscaping materials.
PeerJ ;2018
PMID

Parajuli A, Grönroos M, Siter N, Puhakka R, Vari HK, Roslund MI, Jumpponen A, Nurminen N, Laitinen OH, Hyöty H, Rajaniemi J, Sinkkonen A
Urbanization Reduces Transfer of Diverse Environmental Microbiota Indoors.
Front Microbiol ;2018
PMID

Stone VM, Hankaniemi MM, Svedin E, Sioofy-Khojine A, Oikarinen S, Hyöty H, Laitinen OH, Hytönen VP, Flodström-Tullberg M
A Coxsackievirus B vaccine protects against virus-induced diabetes in an experimental mouse model of type 1 diabetes.
Diabetologia ;61(2)476-481, 2018
PMID

Lietzen N, An LTT, Jaakkola MK, Kallionpää H, Oikarinen S, Mykkänen J, Knip M, Veijola R, Ilonen J, Toppari J, Hyöty H, Lahesmaa R, Elo LL
Enterovirus-associated changes in blood transcriptomic profiles of children with genetic susceptibility to type 1 diabetes.
Diabetologia ;61(2)381-388, 2018
PMID

Saarinen NVV, Laiho JE, Richardson SJ, Zeissler M, Stone VM, Marjomäki V, Kantoluoto T, Horwitz MS, Sioofy-Khojine A, Honkimaa A, Hankaniemi MM, Flodström-Tullberg M, Hyöty H, Hytönen VP, Laitinen OH
A novel rat CVB1-VP1 monoclonal antibody 3A6 detects a broad range of enteroviruses.
Sci Rep ;8(1)33, 2018
PMID

Viskari H, Oikarinen S, Hoppu S, Vuorinen T, Huhtala H, Toppari J, Veijola R, Ilonen J, Knip M, Hyöty H
Live attenuated enterovirus vaccine (OPV) is not associated with islet autoimmunity in children with genetic susceptibility to type 1 diabetes: prospective cohort study.
Diabetologia ;61(1)203-209, 2018
PMID

Parajuli A, Grönroos M, Kauppi S, Płociniczak T, Roslund MI, Galitskaya P, Laitinen OH, Hyöty H, Jumpponen A, Strömmer R, Romantschuk M, Hui N, Sinkkonen A
The abundance of health-associated bacteria is altered in PAH polluted soils-Implications for health in urban areas?
PLoS One ;12(11)e0187852, 2017
PMID

Cinek O, Kramna L, Lin J, Oikarinen S, Kolarova K, Ilonen J, Simell O, Veijola R, Autio R, Hyöty H
Imbalance of bacteriome profiles within the Finnish Diabetes Prediction and Prevention study: Parallel use of 16S profiling and virome sequencing in stool samples from children with islet autoimmunity and matched controls.
Pediatr Diabetes ;18(7)588-598, 2017
PMID

Hankaniemi MM, Laitinen OH, Stone VM, Sioofy-Khojine A, Määttä JAE, Larsson PG, Marjomäki V, Hyöty H, Flodström-Tullberg M, Hytönen VP
Optimized production and purification of Coxsackievirus B1 vaccine and its preclinical evaluation in a mouse model.
Vaccine ;35(30)3718-3725, 2017
PMID

Lin J, Kramna L, Autio R, Hyöty H, Nykter M, Cinek O
Vipie: web pipeline for parallel characterization of viral populations from multiple NGS samples.
BMC Genomics ;18(1)378, 2017
PMID

Honkanen H, Oikarinen S, Nurminen N, Laitinen OH, Huhtala H, Lehtonen J, Ruokoranta T, Hankaniemi MM, Lecouturier V, Almond JW, Tauriainen S, Simell O, Ilonen J, Veijola R, Viskari H, Knip M, Hyöty H
Detection of enteroviruses in stools precedes islet autoimmunity by several months: possible evidence for slowly operating mechanisms in virus-induced autoimmunity.
Diabetologia ;60(3)424-431, 2017
PMID

Campbell-Thompson ML, Atkinson MA, Butler AE, Giepmans BN, von Herrath MG, Hyöty H, Kay TW, Morgan NG, Powers AC, Pugliese A, Richardson SJ, In't Veld PA
Re-addressing the 2013 consensus guidelines for the diagnosis of insulitis in human type 1 diabetes: is change necessary?
Diabetologia ;60(4)753-755, 2017
PMID

Kantola K, Hedman L, Tanner L, Simell V, Mäkinen M, Partanen J, Sadeghi M, Veijola R, Knip M, Ilonen J, Hyöty H, Toppari J, Simell O, Hedman K, Söderlund-Venermo M
Correction: B-Cell Responses to Human Bocaviruses 1-4: New Insights from a Childhood Follow-Up Study.
PLoS One ;12(2)e0172078, 2017
PMID

Busse N, Paroni F, Richardson SJ, Laiho JE, Oikarinen M, Frisk G, Hyöty H, de Koning E, Morgan NG, Maedler K
Detection and localization of viral infection in the pancreas of patients with type 1 diabetes using short fluorescently-labelled oligonucleotide probes.
Oncotarget ;8(8)12620-12636, 2017
PMID

Viisanen T, Ihantola EL, Näntö-Salonen K, Hyöty H, Nurminen N, Selvenius J, Juutilainen A, Moilanen L, Pihlajamäki J, Veijola R, Toppari J, Knip M, Ilonen J, Kinnunen T
Circulating CXCR5+PD-1+ICOS+ Follicular T Helper Cells Are Increased Close to the Diagnosis of Type 1 Diabetes in Children With Multiple Autoantibodies.
Diabetes ;66(2)437-447, 2017
PMID

 
Maintained by: med.info@uta.fi
Last update: 1.10.2018 13.21 Muokkaa

University of Tampere
+358 3 355 111
registry@uta.fi


FINEEC Audited HR Excellence in Research

THE UNIVERSITY
Research
Admissions
Studies
News
Cooperation and Services
About Us

CURRENT ISSUES
Research & Study
Tampere3
Vacancies

SERVICES
Administration
Career Services
Finnish Social Science Data Archive
Centre for International Education
IT services
Language Centre
Language Services
Library
Registrar's Office
Registry
Sports Activities
» more

STUDIES
Teaching schedules
Curricula guides
Student's Desktop

ONLINE SERVICES
Andor search
Renew your loans
UTA intranet
Office 365 webmail
Uta webmail
Moodle
NettiOpsu
NettiKatti
TamPub
Electronic exam service
Examination results