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[Description]
[Members]
[Organisation]
[Contact Information]
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University of Ferrara, Italy, Center of Bioacoustics
The role of
this partner within the project is to provide expertise in cell culture
techniques, to enablebiocompatibility and effectiveness studies to be carried
out on the materials and drugs used.Workpackage 4 “Efficacy and
bio-compatibility of NTF, AO, and bio-polymer (in-vitro)”.WP
leaderAlessandro Martini. Also locally responsible
for WP6.
The Centre
of Bioacoustics is an inter-disciplinary centre placed between the Department of
Audiology and the Department of Human Anatomy at the University of Ferrara. It
was established in 1998, to investigate molecular processes related to
ototoxicity, cell differentiation, and apoptosis. It has a broad range of
facilities for these experiments, including laser microscopes, fluorescent
microscopes, a spectrometer, a cytoflowmeter, and a HPLC unit.
Key Personnel
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Professor Alessandro Martini,
is a Specialist in Audiology and is Director of the Bioacustic Centre. He is
responsible for the audiological service at the University of Ferrara. He
was nominated in 1986 Professor of Paediatric Otolaryngology and in 1989
Professor of Audiology, for Padua University. He has been one active
participant in BIOMED 2 (PL950353: A European Working Groups on Geneticts of
Hearing Impairment, 1996-99), in TELETHON (Project EC473 A genetic of
otosclerosis: phenotopic characterization, family collection and linkage
studies, 1997). His laboratory is using frequently an immortal mouse hair
cell line in studies concerning hair cell functions. This experience will
allow the group to develop an immortal cell line of SGC’s for use in the
BIO-EAR project. Prof. Martini has an active research laboratory with 2
laboratory technicians and 5 researchers. |
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Dr Stavros Hatzopoulos
holds a Ph.D. degree from Worcester Polytechnic
Institute, Massachusetts USA, in Audiological Engineering. He been
involved in auditory research and bio-informatics since 1988, and his
particular interests include technologies related to the field of
otoacoustic emissions and auditory evoked responses in animal models and
newborn subjects. Dr Hatzopoulos is responsible for the in-vivo studies
of the Center of Bioacoustics. He is a member of the American Society of
Audiology (ASA) and the Institute of Electric and Electronic Engineers
(IEEE). He has been involved in previous BIOMED projects such as :
project HEAR (PL950353: A European Working Group on the Genetics of
Hearing Impairment, 1996-99) ; project GENDEAF (European Thematic
Network on Genetic Deafness 2001-); and project AHEAD (Advancement of
Hearing Assessment Methods and Devices 1996-1999).
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Maurizio Previati MS works on signal
transduction during neuronal and neuroepithelial differentiation (PC12,
OCK-3, focusing on PLC activity, PKC activation), inositide, inositol and
diradylglycerol production, kinase recruitment and redox balance after
stimulation with neurotrophic factors and drugs (aminoglycosides and
chemotherapeutics). |
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