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University of Michigan, USA Kresge Hearing Institute. The role of the department within the programme will be quality management and toxicity testing.Workpackage 3 “Toxicity limits of NTF, AO, and bio-polymers (in-vivo)”. WP leader Professor Josef Miller. Also locally responsible for WP2, WP3. Kresge Hearing Research Institute, which consists of 620 square feet of laboratory and office space. It contains three dedicated surgical areas, two electrically-shielded sound proof booths for electrophysiological (ABR) recordings, and complete facilities for sterile animal surgery and post-operative care. It also contains a preparation facility and recording system for studies of cochlear blood flow, including all necessary laser-Doppler and monitoring facilities. The ABR facility is shortly to be replaced with a state of the art Tucker- Davis system. The Kresge Institute provides access to all the modern research technology required for the project, including: the anatomy laboratory, imaging laboratory, molecular biology core, and computing and statistical core facilities. Professor Miller has several researchers working in his laboratory and 6 laboratory technicians. Key Personnel
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